Institute for Global Health, University College London, 30 Guilford Street, London, WC1N 1EH, United Kingdom.
Department of Health Policy, Planning and Management, School of Public Health, University of Ghana, Legon, Accra, Ghana.
Pan Afr Med J. 2021 Mar 30;38:317. doi: 10.11604/pamj.2021.38.317.28335. eCollection 2021.
the provision of antiretroviral treatment (ART) to people living with HIV/AIDS (PLHIV) has improved their life expectancy significantly. Conversely, this has been associated with an elevated risk of cardiovascular diseases. Yet, research to improve understanding of cardiovascular risk factors among PLHIV remains limited. This study examines the prevalence and correlates of cardiovascular risk factors among PLHIV at the Korle Bu Teaching Hospital (KBTH) in Accra, Ghana.
a cross-sectional study was conducted at the KBTH, Accra, Ghana. Patients were recruited from the adult HIV outpatient clinic at the infectious disease unit, KBTH. The sample comprised 525 PLHIV, aged 18 years and above. Data were analysed using descriptive statistics and a multivariable binary logistic regression.
among the patients, 9.7% (n=51) had hypertension and 15.6% (n=82) were reportedly patients with diabetes. With respect to the serum lipid profile, 24.8% (n=130) had hypertriglyceridemia, 49.1% (n=258) had hypercholesterolemia, 26.3% (138) had low high-density lipoprotein, and high low-density lipoprotein was found in 27.2% (n=143) of the cohort. The multivariable binary logistic regression results showed that being unemployed, underweight, being on ART, being male, having a higher level of education, and not having health insurance subscription significantly increased the odds of cardiovascular risk factors among the patients.
current findings buttress concern for elevated risk of cardiovascular diseases among PLHIV and calls for increased attention for comprehensive care that includes the prevention and management of cardiovascular diseases and its risk factors among this vulnerable group.
为艾滋病毒/艾滋病感染者(PLHIV)提供抗逆转录病毒治疗(ART)大大提高了他们的预期寿命。相反,这与心血管疾病风险的增加有关。然而,关于改善 PLHIV 心血管风险因素的研究仍然有限。本研究在加纳阿克拉的科勒布教学医院(KBTH)检查了 PLHIV 心血管风险因素的流行率和相关性。
在加纳阿克拉的 KBTH 进行了一项横断面研究。从传染病科 KBTH 的成人艾滋病毒门诊诊所招募了患者。该样本包括 525 名年龄在 18 岁及以上的 PLHIV。使用描述性统计和多变量二项逻辑回归分析数据。
在患者中,9.7%(n=51)患有高血压,15.6%(n=82)据报道患有糖尿病。关于血清脂质谱,24.8%(n=130)有高甘油三酯血症,49.1%(n=258)有高胆固醇血症,26.3%(138)有低高密度脂蛋白血症,27.2%(n=143)的队列中有高低密度脂蛋白血症。多变量二项逻辑回归结果表明,失业、体重不足、正在接受 ART、男性、受教育程度较高和没有医疗保险订阅显著增加了患者心血管风险因素的几率。
目前的研究结果证实了 PLHIV 患心血管疾病风险增加的担忧,并呼吁加强对包括预防和管理心血管疾病及其风险因素在内的全面护理的关注,以关注这一弱势群体。