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卡塔尔急性、慢性和神经性疼痛管理的专家评审与建议

Expert review and recommendations for the management of acute, chronic, and neuropathic pain in Qatar.

作者信息

Elmoheen Amr, Nazal Abdullah F, Zubaidi Osman, Siddiqui Urooj A, Alhatou Mohammed

机构信息

Emergency Medicine Department, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar

Pain Management Section, Department of Anesthesiology, ICU and Perioperative Medicine, Al Wakra Hospital, Hamad Medical Corporation, Doha, Qatar.

出版信息

Qatar Med J. 2021 Jul 7;2021(2):19. doi: 10.5339/qmj.2021.19. eCollection 2021.

Abstract

BACKGROUND

Pain management is an evolving area of expertise in Qatar. Gaps in knowledge, inadequate training for physicians and nurses, and the absence of policies/guidelines are the main barriers to effective pain management in Qatar. In addition, the use of certain pain medication, especially opioids, is highly regulated, limiting their availability in outpatient pain management. These factors are responsible for the undertreatment of pain in Qatar. This study aimed to standardize evidence-based local recommendations for pharmacological treatment of pain in Qatar.

METHODS

An expert panel of physicians from different disciplines, with experience in diagnosis and treatment of the three pain types (i.e., acute, chronic, and neuropathic), was convened for two face-to-face meetings in Doha, Qatar, on November 29, 2019, and on February 22, 2020, with subsequent virtual meetings. A literature search was performed on Medline and Google Scholar databases from inception till December 2019, and all relevant articles were selected. Based on these articles and repeated feedback from the authors, the final pain treatment protocols were developed.

RESULTS

Recommendations for the treatment of acute pain, based on pain severity, followed three approaches: acetaminophen/paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs) for mild pain and moderate pain and referral to a pain specialist for severe pain. Acetaminophen/paracetamol or NSAIDs is recommended for chronic pain, and the use of opioids was strongly discouraged because of its long-term side effects. For neuropathic pain, tricyclic antidepressants or gabapentin or pregabalin or serotonin-norepinephrine reuptake inhibitors were recommended first-line agents. Non-responders must be referred to neurologists or a pain specialist.

CONCLUSION

The expert panel provides recommendations for the management of acute, chronic, and neuropathic pain based on international guidelines adapted to local practice and treatment availability in Qatar. More importantly, the panel has recommended taking extreme caution in the use of opioids for long-term management of chronic pain and to refer the patient to a pain specialist clinician as required.

摘要

背景

疼痛管理是卡塔尔一个不断发展的专业领域。知识空白、医生和护士培训不足以及缺乏政策/指南是卡塔尔有效疼痛管理的主要障碍。此外,某些止痛药物的使用,尤其是阿片类药物,受到严格监管,限制了其在门诊疼痛管理中的可用性。这些因素导致卡塔尔的疼痛治疗不足。本研究旨在规范卡塔尔基于证据的疼痛药物治疗的本地建议。

方法

2019年11月29日和2020年2月22日,在卡塔尔多哈召开了由来自不同学科、具有三种疼痛类型(即急性、慢性和神经性)诊断和治疗经验的医生组成的专家小组进行了两次面对面会议,随后进行了虚拟会议。从创刊至2019年12月在Medline和谷歌学术数据库上进行了文献检索,并挑选了所有相关文章。基于这些文章和作者的反复反馈,制定了最终的疼痛治疗方案。

结果

基于疼痛严重程度的急性疼痛治疗建议遵循三种方法:轻度和中度疼痛使用对乙酰氨基酚/扑热息痛或非甾体抗炎药(NSAIDs),重度疼痛转诊至疼痛专科医生。慢性疼痛建议使用对乙酰氨基酚/扑热息痛或NSAIDs,由于其长期副作用,强烈不鼓励使用阿片类药物。对于神经性疼痛,推荐三环类抗抑郁药或加巴喷丁或普瑞巴林或5-羟色胺-去甲肾上腺素再摄取抑制剂作为一线药物。无反应者必须转诊至神经科医生或疼痛专科医生。

结论

专家小组根据适用于卡塔尔当地实践和治疗可用性的国际指南,为急性、慢性和神经性疼痛的管理提供了建议。更重要的是,该小组建议在使用阿片类药物进行慢性疼痛的长期管理时要格外谨慎,并根据需要将患者转诊至疼痛专科临床医生处。

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本文引用的文献

3
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4
Emergency department pain management: beyond opioids.
Emerg Med Pract. 2019 Nov;21(11):1-24. Epub 2019 Nov 1.
5
Intranasal sufentanil versus intravenous morphine for acute severe trauma pain: A double-blind randomized non-inferiority study.
PLoS Med. 2019 Jul 16;16(7):e1002849. doi: 10.1371/journal.pmed.1002849. eCollection 2019 Jul.
8
A Comprehensive Algorithm for Management of Neuropathic Pain.
Pain Med. 2019 Jun 1;20(Suppl 1):S2-S12. doi: 10.1093/pm/pnz075.
9
Intranasal hydromorphone for treatment of acute pain in children: A pilot study.
Am J Emerg Med. 2019 Jun;37(6):1128-1132. doi: 10.1016/j.ajem.2019.03.013. Epub 2019 Mar 13.
10
Randomized Trial of Intravenous Lidocaine Versus Hydromorphone for Acute Abdominal Pain in the Emergency Department.
Ann Emerg Med. 2019 Aug;74(2):233-240. doi: 10.1016/j.annemergmed.2019.01.021. Epub 2019 Feb 26.

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