Ebner Daniel K, Malouff Timothy D, Frank Steven J, Koto Masashi
Hospital of the National Institutes of Quantum and Radiological Science and Technology (QST Hospital), Chiba, Japan.
Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USA.
Int J Part Ther. 2021 Jun 25;8(1):273-284. doi: 10.14338/IJPT-D-20-00076. eCollection 2021 Summer.
Particle irradiation is suitable for resistant histologies owing to a combination of improved dose delivery with potential radiobiologic advantages in high linear energy transfer radiation. Within the head and neck, adenoid cystic carcinoma and mucosal melanoma are two such histologies, being radioresistant and lying closely proximal to critical structures. Here, we review the use of particle irradiation for adenoid cystic carcinoma and mucosal melanoma of the head and neck.
由于在高线性能量传递辐射中改善了剂量传递并具有潜在的放射生物学优势,粒子辐射适用于抗辐射组织学类型。在头颈部,腺样囊性癌和黏膜黑色素瘤就是这样两种组织学类型,它们具有放射抗性且紧邻关键结构。在此,我们综述粒子辐射在头颈部腺样囊性癌和黏膜黑色素瘤治疗中的应用。