Dewenter Ina, Otto Sven, Kakoschke Tamara Katharina, Smolka Wenko, Obermeier Katharina Theresa
Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Ludwig Maximilians University, D-80337 Munich, Germany.
J Clin Med. 2023 Feb 12;12(4):1463. doi: 10.3390/jcm12041463.
With an incidence of 3-4.5 cases per million, adenoid cystic carcinoma (ACC) of the head and neck is one of the most common tumors of the parotid and sublingual salivary glands. In the clinical course, ACC is shown to have an aggressive long-term behavior, which leads to the fact that radical surgical resection of the tumor with tumor-free margins remains the "gold standard" in treating ACC. Particle radiation therapy and systemic molecular biological approaches offer new treatment options. However, risk factors for the formation and prognosis of ACC have not yet been clearly identified. The aim of the present review was to investigate long-term experience of diagnosis and treatment as well as risk and prognostic factors for occurrence and outcome of ACC.
头颈部腺样囊性癌（ACC）的发病率为每百万人口中有3 - 4.5例，是腮腺和舌下唾液腺最常见的肿瘤之一。在临床过程中，ACC表现出具有侵袭性的长期行为，这导致肿瘤切缘无瘤的根治性手术切除仍是治疗ACC的“金标准”。粒子放射治疗和全身分子生物学方法提供了新的治疗选择。然而，ACC形成和预后的危险因素尚未明确。本综述的目的是研究ACC诊断和治疗的长期经验以及发生和转归的风险和预后因素。
