慢性胰腺炎中的胆汁脂质代谢：脂肪泻的影响
Biliary lipid metabolism in chronic pancreatitis: influence of steatorrhoea.
作者信息
Einarsson K, Angelin B, Johansson C
机构信息
Department of Medicine, Karolinska Institute, Huddinge University Hospital, Sweden.
出版信息
Gut. 1987 Nov;28(11):1495-9. doi: 10.1136/gut.28.11.1495.
Kinetics of [24-14C] cholic acid and [24-14C] chenodeoxycholic acid and biliary lipid composition were determined in patients with chronic alcoholic pancreatitis with (n = 8) and without (n = 8) steatorrhoea. Pool sizes, syntheses and fractional catabolic rates of the two bile acids were not significantly different from corresponding values in healthy controls. Biliary lipid composition was normal in patients without steatorrhoea. Patients with steatorrhoea, on the other hand, had lower cholesterol saturation of bile than corresponding controls. This is probably because of malabsorption of cholesterol.
对伴有（n = 8）和不伴有（n = 8）脂肪泻的慢性酒精性胰腺炎患者，测定了[24-¹⁴C]胆酸和[24-¹⁴C]鹅去氧胆酸的动力学以及胆汁脂质组成。两种胆汁酸的池大小、合成及分解代谢率与健康对照者的相应值无显著差异。无脂肪泻的患者胆汁脂质组成正常。另一方面，有脂肪泻的患者胆汁胆固醇饱和度低于相应对照者。这可能是由于胆固醇吸收不良所致。
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