College of Pharmaceutical Science & Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou, 310014, P. R. China.
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371, Singapore.
Chem Asian J. 2021 Oct 4;16(19):2753-2772. doi: 10.1002/asia.202100686. Epub 2021 Jul 29.
Oxidation represents one of the most important and practical chemical transformations for both organic synthesis, material science and pharmaceutical area. Among the existing strategies, molybdenum/tungsten-based heteropoly salts involved oxidations with low-cost and environmentally benign terminal oxidant and thus have attracted considerable attention in recent years. In this review, we have summarized the recent development of heteropoly salts utilized in oxidations, mainly the peroxomolybdates and peroxotungstates. We wish to highlight the progress made in the past 20 years of this field. Three categories are classified according to the aggregation state of metal oxides. Special attention is paid to the catalytically active peroxometalate species generated during the oxidation process. It is helpful to shed light on the common features that enable highly efficient and selective oxidations. We aim to inspire fellow chemists to explore more functional metalates for catalytic oxidations, especially asymmetric versions. Meanwhile, we attempt to understand the design principles for the discovery of more efficient, selective and economical catalytic systems.
氧化是有机合成、材料科学和制药领域中最重要和最实用的化学转化之一。在现有的策略中，钼/钨基杂多酸盐涉及使用低成本和环境友好的终端氧化剂进行氧化，因此近年来引起了相当大的关注。在这篇综述中，我们总结了近年来用于氧化的杂多酸盐的最新发展，主要是过氧钼酸盐和过氧钨酸盐。我们希望强调过去 20 年来在这一领域取得的进展。根据金属氧化物的聚集状态，将其分为三类。特别关注氧化过程中生成的催化活性过氧金属酸盐物种。这有助于揭示实现高效和选择性氧化的共同特征。我们的目标是启发化学家探索更多用于催化氧化的功能性金属盐，特别是不对称版本。同时，我们试图理解发现更有效、选择性和经济的催化体系的设计原则。
