Modi Biren P, Galloway David P, Gura Kathleen, Nucci Anita, Plogsted Steven, Tucker Alyssa, Wales Paul W
Center for Advanced Intestinal Rehabilitation, Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Division of Gastroenterology, Hepatology and Nutrition, University of Alabama at Birmingham, Birmingham, Alabama, USA.
JPEN J Parenter Enteral Nutr. 2022 Jan;46(1):42-59. doi: 10.1002/jpen.2232. Epub 2021 Sep 15.
Pediatric intestinal failure (PIF) is a relatively rare disease entity that requires focused interdisciplinary care and specialized nutrition management. There has long been a lack of consensus in the definition of key terms related to PIF because of its rarity and a plethora of small studies rather than large trials. As such, the American Society for Parenteral and Enteral Nutrition (ASPEN) PIF Section, composed of clinicians from a variety of disciplines caring for children with intestinal failure, is uniquely poised to provide insight into this definition void. This document is the product of an effort by the Section to create evidence-based consensus definitions, with the goal of allowing for appropriate comparisons between clinical studies and measurement of long-term patient outcomes. This paper has been approved by the ASPEN Board of Directors.
小儿肠衰竭（PIF）是一种相对罕见的疾病实体，需要多学科的专门护理和特殊营养管理。由于其罕见性以及大量的小型研究而非大型试验，长期以来在与PIF相关的关键术语定义上缺乏共识。因此，由照顾肠衰竭患儿的各学科临床医生组成的美国肠外与肠内营养学会（ASPEN）PIF分会，特别适合为填补这一定义空白提供见解。本文件是该分会努力制定基于证据的共识定义的成果，目的是便于临床研究之间进行适当比较并衡量患者长期预后。本文已获ASPEN董事会批准。
