Blinder B J, Chaitin B F, Hagman J
Department of Psychiatry and Human Behavior, College of Medicine, University of California, Irvine.
Hillside J Clin Psychiatry. 1987;9(2):211-6.
Evaluations of neuroendocrine abnormalities and possible relationship to major affective disorder in normal weight bulimic women have utilized the Dexamethasone Suppression Test (DST). In our sample of 29 bulimic women, 59% showed DST nonsuppression (DSTNS). Two diagnostic correlates were significant in relation to DSTNS: prior history of anorexia nervosa and current clinical DSM III diagnosis of depression. Eating Attitudes Test (EAT) scores were also significantly higher in the DSTNS group. The findings suggest that more extensive psychiatric disorder and ingestive abnormalities may be present in this subgroup of normal weight bulimic women who exhibit DST nonsuppression.
对正常体重的贪食症女性的神经内分泌异常及其与重性情感障碍可能存在的关系进行评估时，采用了地塞米松抑制试验（DST）。在我们抽取的29名贪食症女性样本中，59%的人显示地塞米松抑制试验无抑制（DSTNS）。与DSTNS相关的两个诊断关联因素具有显著意义：神经性厌食症既往史以及当前临床依据《精神疾病诊断与统计手册》第三版对抑郁症的诊断。地塞米松抑制试验无抑制组的饮食态度测试（EAT）得分也显著更高。研究结果表明，在表现出地塞米松抑制试验无抑制的正常体重贪食症女性这一亚组中，可能存在更广泛的精神障碍和摄食异常。
