Western Sydney University, Torrens University, Sydney, Nutrition Australia.
Nutr Health. 2022 Jun;28(2):265-269. doi: 10.1177/02601060211019669. Epub 2021 Jul 21.
Neuropathic pain is a condition caused by a lesion or disease of the somatosensory nervous system. It may present as debilitating pain with a sensation of burning and electric-like symptoms and is often difficult to manage effectively. Although pharmacological medications are the first line of treatment, multidisciplinary teams are sometimes required to provide appropriate treatment to improve quality of life and overall wellbeing.
The aim of this study is to present a case of post herpetic neuralgia relieved successfully by the compound palmitoylethanolamide (PEA) - a natural alternative to pharmacological pain relief.
We present the case of a 67 year-old male with ongoing post-herpetic neuralgia, over a 3-year period, as a result of complications from shingles (herpes zoster). Previous studies on the relationship between PEA and neuropathy were reviewed, with an attempt to discuss the possible underlying mechanism of PEA on neuropathic pain.
PEA demonstrated effective pain relief within 48 hours at an administered daily dose of 900 mg (10 mg/kg).
PEA may offer a valid nutraceutical treatment for practitioners.
神经病理性疼痛是由躯体感觉神经系统的损伤或疾病引起的一种病症。它可能表现为使人虚弱的疼痛，伴有烧灼感和电击样症状，通常很难有效控制。尽管药物治疗是首选，但有时需要多学科团队提供适当的治疗，以提高生活质量和整体幸福感。
本研究旨在介绍一例带状疱疹后神经痛成功缓解的病例，该病例通过使用复合棕榈酸乙酯（PEA）得到缓解，PEA 是一种替代药物缓解疼痛的天然选择。
我们报告了一例 67 岁男性的病例，他因带状疱疹（带状疱疹）的并发症持续存在带状疱疹后神经痛，已超过 3 年。我们回顾了 PEA 与神经病变之间关系的先前研究，并试图讨论 PEA 对神经病理性疼痛的可能潜在作用机制。
在每天给予 900 毫克（10 毫克/公斤）的剂量后，PEA 在 48 小时内显示出有效的止痛效果。
PEA 可能为从业者提供一种有效的营养治疗方法。
