Department of General Surgery, Faculty of Medicine, Mustafa Kemal University, Hatay,, Turkey.
Department of Medical Biochemistry, Reyhanlı State Hospital, Hatay, Turkey.
Niger J Clin Pract. 2021 Jul;24(7):993-996. doi: 10.4103/njcp.njcp_370_19.
Fat accumulation in the visceral and subcutaneous regions can trigger fat necrosis during acute pancreatitis (AP).
We investigated the role of visceral and subcutaneous fat in acute pancreatitis. In this study, we investigated the role of visceral and subcutaneous fat to understand the efficiency of adipose tissue in the AP.
Computed tomography of 68 patients and 68 healthy at the level of L4-5 intervertebral disc were analyzed for body adiposity composition using designated software. Body subcutaneous and visceral composition was measured by using the designated software of the CT.
Visceral fat was higher in the control group (198 ± 146) than the group of the AP (155 ± 118) (P = 0.038), whereas the subcutaneous fat was found higher in the AP instead (292 ± 133 to 139 ± 102; P = 0,001). Visceral fat (B = 0,29; P = 0,0013), gender (male) (B = -0.3; P = 0.0122), age (B = 0.274; P = 0.0087), and complication (B = -0.229; P = 0.007) predicted the subcutaneous fat as the dependent variable. In the receiver operating characteristic (ROC), the area under curve was 0.562 (0.402-0.636; 95% CI, P = 0.038) for the visceral fat, while it was 0.906 (0.824-0.962; 95% CI, P < 0.0001) for the subcutaneous fat. Its cutoff was calculated as 183.7 for subcutaneous fat.
Visceral fat analysis showed a contradiction according to subcutaneous fat that AP was strongly associated with subcutaneous one. The result supports that visceral and subcutaneous fat tissues should have different path of inflammation affecting the AP.
内脏和皮下脂肪堆积可在急性胰腺炎（AP）期间引发脂肪坏死。
我们研究了内脏和皮下脂肪在急性胰腺炎中的作用。在这项研究中，我们研究了内脏和皮下脂肪的作用，以了解脂肪组织在 AP 中的效率。
对 68 名患者和 68 名健康成年人在 L4-5 椎间盘水平进行了计算机断层扫描，使用指定软件分析了身体脂肪成分。使用 CT 指定软件测量了身体的皮下和内脏组成。
对照组的内脏脂肪（198±146）高于 AP 组（155±118）（P=0.038），而 AP 组的皮下脂肪较高（292±133 至 139±102；P=0.001）。内脏脂肪（B=0.29；P=0.0013）、性别（男性）（B=-0.3；P=0.0122）、年龄（B=0.274；P=0.0087）和并发症（B=-0.229；P=0.007）预测了作为因变量的皮下脂肪。在接受者操作特征（ROC）中，曲线下面积为内脏脂肪 0.562（0.402-0.636；95%CI，P=0.038），而皮下脂肪为 0.906（0.824-0.962；95%CI，P<0.0001）。皮下脂肪的截断值计算为 183.7。
根据与皮下脂肪的矛盾分析，内脏脂肪表明 AP 与皮下脂肪强烈相关。该结果支持内脏和皮下脂肪组织应具有不同的炎症途径，影响 AP。
