与大血管血管炎相关的周边溃疡性角膜炎

Peripheral Ulcerative Keratitis Associated With Large Vessel Vasculitis.

作者信息

Uchida Shun, Kaji Yuki, Ui Mutushito, Kawashima Hirotoshi, Usui Tomohiko, Ohira Yoshiyuki

机构信息

General Medicine, International University of Health and Welfare Narita Hospital, Chiba, JPN.

Allergy and Rheumatology, International University of Health and Welfare Narita Hospital, Chiba, JPN.

出版信息

Cureus. 2021 Jun 20;13(6):e15767. doi: 10.7759/cureus.15767. eCollection 2021 Jun.

DOI:10.7759/cureus.15767

PMID:34290940

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8290306/

Abstract

Peripheral ulcerative keratitis (PUK) is a non-infectious ulcer at the peripheral corneal stroma. Autoimmune diseases can cause PUK, but PUK caused by large vessel vasculitis (LVV) has rarely been reported. We report the case of a 71-year-old woman with complaints of low-grade fever and left eye pain. Ophthalmologic examination revealed PUK in the left eye, and we diagnosed LVV by F-fluorodeoxyglucose-positron emission tomography (FDG-PET) findings. The patient was treated with topical betamethasone eye drops for PUK and oral prednisolone for LVV. This case suggests that LVV can cause PUK.

摘要

周边溃疡性角膜炎（PUK）是一种发生于周边角膜基质的非感染性溃疡。自身免疫性疾病可导致PUK，但由大血管血管炎（LVV）引起的PUK鲜有报道。我们报告一例71岁女性患者，主诉低热和左眼疼痛。眼科检查发现左眼有PUK，我们通过氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）结果诊断为LVV。该患者接受了局部倍他米松滴眼液治疗PUK以及口服泼尼松龙治疗LVV。此病例提示LVV可导致PUK。