McNamara Niamh B, Miron Veronique E
Centre for Discovery Brain Sciences, Chancellor's Building, The University of Edinburgh, Edinburgh, UK; United Kingdom Dementia Research Institute at The University of Edinburgh, Edinburgh, UK; Medical Research Council Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
Centre for Discovery Brain Sciences, Chancellor's Building, The University of Edinburgh, Edinburgh, UK; United Kingdom Dementia Research Institute at The University of Edinburgh, Edinburgh, UK; Medical Research Council Centre for Reproductive Health, The Queen's Medical Research Institute, The University of Edinburgh, Edinburgh, UK.
Neuron. 2021 Jul 21;109(14):2204-2206. doi: 10.1016/j.neuron.2021.06.024.
In this issue of Neuron, Chen et al. (2021) reveal dynamic changes in myelin in an Alzheimer's disease (AD) mouse model. Enhancing myelination genetically or pharmacologically improves cognition in this model, supporting myelin as a therapeutic target for AD.
在本期《神经元》杂志中，陈等人（2021年）揭示了阿尔茨海默病（AD）小鼠模型中髓磷脂的动态变化。在该模型中，通过基因或药物手段增强髓鞘形成可改善认知，这支持了将髓磷脂作为AD的治疗靶点。
