Marneweck Michelle, Grafton Scott T
Department of Human Physiology, University of Oregon, Eugene, OR 97403-1249, USA.
Monash Biomedical Imaging, Monash University, Melbourne, Victoria 3168, Australia.
Cereb Cortex Commun. 2020 Oct 30;1(1):tgaa080. doi: 10.1093/texcom/tgaa080. eCollection 2020.
Humans are seamless in their ability to efficiently and reliably generate fingertip forces to gracefully interact with objects. Such interactions rarely end in awkward outcomes like spilling, crushing, or tilting given advanced motor planning. Here we combine multiband imaging with deconvolution- and Bayesian pattern component modeling of functional magnetic resonance imaging data and in-scanner kinematics, revealing compelling evidence that the human brain differentially represents preparatory information for skillful object interactions depending on the saliency of visual cues. Earlier patterned activity was particularly evident in ventral visual processing stream-, but also selectively in dorsal visual processing stream and cerebellum in conditions of heightened uncertainty when an object's superficial shape was incompatible rather than compatible with a key underlying object feature.
人类能够高效且可靠地产生指尖力量，以便与物体进行优雅互动，这一能力堪称完美。鉴于先进的运动规划，此类互动很少会以诸如洒落、挤压或倾倒等尴尬结果告终。在此，我们将多波段成像与功能磁共振成像数据及扫描仪内运动学的反卷积和贝叶斯模式成分建模相结合，揭示了令人信服的证据，即人类大脑根据视觉线索的显著性，对熟练物体互动的准备信息进行差异表征。早期的模式化活动在腹侧视觉处理流中尤为明显，但在物体表面形状与关键潜在物体特征不兼容而非兼容时，在不确定性增加的情况下，背侧视觉处理流和小脑中也有选择性地体现。
