Grand Challenges in Musculoskeletal Pain Research: Chronicity, Comorbidity, Immune Regulation, Sex Differences, Diagnosis, and Treatment Opportunities.
作者信息
Ren Ke
机构信息
Department of Neural and Pain Sciences, School of Dentistry, University of Maryland, Baltimore, MD, United States.
Program in Neuroscience, University of Maryland, Baltimore, MD, United States.
出版信息
Front Pain Res (Lausanne). 2020 Oct;1. doi: 10.3389/fpain.2020.575479. Epub 2020 Oct 23.
Abstract
摘要
相似文献
1
Grand Challenges in Musculoskeletal Pain Research: Chronicity, Comorbidity, Immune Regulation, Sex Differences, Diagnosis, and Treatment Opportunities.肌肉骨骼疼痛研究中的重大挑战：慢性化、合并症、免疫调节、性别差异、诊断及治疗机遇
Front Pain Res (Lausanne). 2020 Oct;1. doi: 10.3389/fpain.2020.575479. Epub 2020 Oct 23.
2
Deconstructing chronicity of musculoskeletal pain: intensity-duration relations, minimal dimensions and clusters of chronicity.解析肌肉骨骼疼痛的慢性特征：强度-持续时间关系、最小维度与慢性特征簇
Scand J Pain. 2018 Jul 26;18(3):363-377. doi: 10.1515/sjpain-2018-0021.
3
From acute musculoskeletal pain to chronic widespread pain and fibromyalgia: application of pain neurophysiology in manual therapy practice.从急性肌肉骨骼疼痛到慢性广泛性疼痛和纤维肌痛：疼痛神经生理学在手法治疗实践中的应用
Man Ther. 2009 Feb;14(1):3-12. doi: 10.1016/j.math.2008.03.001. Epub 2008 Jun 3.
4
Subgroups of musculoskeletal pain patients and their psychobiological patterns - the LOGIN study protocol.肌肉骨骼疼痛患者亚组及其心理生物学模式 - LOGIN 研究方案。
BMC Musculoskelet Disord. 2012 Aug 3;13:136. doi: 10.1186/1471-2474-13-136.
5
Do comorbid fibromyalgia diagnoses change after a functional restoration program in patients with chronic disabling occupational musculoskeletal disorders?在患有慢性致残性职业性肌肉骨骼疾病的患者中，经过功能恢复计划后，共病纤维肌痛的诊断会发生变化吗？
Spine (Phila Pa 1976). 2014 Aug 1;39(17):1393-400. doi: 10.1097/BRS.0000000000000406.
6
Comorbid symptoms of depression and musculoskeletal pain and risk of long term sickness absence.抑郁和肌肉骨骼疼痛的共病症状与长期病假风险。
BMC Public Health. 2018 Aug 6;18(1):981. doi: 10.1186/s12889-018-5740-y.
7
The epidemiology of chronic generalized musculoskeletal pain.慢性广泛性肌肉骨骼疼痛的流行病学
Best Pract Res Clin Rheumatol. 2003 Aug;17(4):547-61. doi: 10.1016/s1521-6942(03)00042-1.
8
The Relation of Physical Comorbidity and Multimorbidity to Fibromyalgia, Widespread Pain, and Fibromyalgia-related Variables.躯体共病和多种疾病与纤维肌痛、广泛性疼痛及纤维肌痛相关变量的关系。
J Rheumatol. 2020 Apr;47(4):624-631. doi: 10.3899/jrheum.190149. Epub 2019 Aug 1.
9
Undiagnosed mood disorders and sleep disturbances in primary care patients with chronic musculoskeletal pain.在患有慢性肌肉骨骼疼痛的初级保健患者中，未确诊的情绪障碍和睡眠障碍。
Pain Med. 2013 Sep;14(9):1416-25. doi: 10.1111/pme.12165. Epub 2013 Jun 6.
10
Prevalence of musculoskeletal disorders is systematically higher in women than in men.肌肉骨骼疾病的患病率在女性中系统性地高于男性。
Clin J Pain. 2006 Oct;22(8):717-24. doi: 10.1097/01.ajp.0000210912.95664.53.
引用本文的文献
1
Mapping cell diversity and dynamics in inflammatory temporomandibular joint osteoarthritis with pain at single-cell resolution.在单细胞分辨率下绘制伴有疼痛的炎性颞下颌关节骨关节炎中的细胞多样性和动态变化。
JCI Insight. 2025 Feb 10;10(3):e184379. doi: 10.1172/jci.insight.184379.
2
How strenuous is esports? Perceived physical exertion and physical state during competitive video gaming.电子竞技的强度有多大？竞技性电子游戏过程中的主观体力消耗和身体状态。
Front Sports Act Living. 2024 Jul 10;6:1370485. doi: 10.3389/fspor.2024.1370485. eCollection 2024.
3
Elevated circulating soluble interleukin-2 receptor (sCD25) level is associated with prefrontal excitatory-inhibitory imbalance in individuals with chronic pain: A proton MRS study.循环中可溶性白细胞介素-2 受体（sCD25）水平升高与慢性疼痛患者前额叶兴奋-抑制失衡有关：一项质子磁共振波谱研究。
Brain Behav Immun. 2024 Aug;120:1-9. doi: 10.1016/j.bbi.2024.05.020. Epub 2024 May 19.
4
Pain-sensorimotor interactions: New perspectives and a new model.疼痛-感觉运动相互作用：新观点与新模型。
Neurobiol Pain. 2024 Jan 20;15:100150. doi: 10.1016/j.ynpai.2024.100150. eCollection 2024 Jan-Jun.
5
A mixed-methods feasibility study of a comorbidity-adapted exercise program for low back pain in older adults (COMEBACK): a protocol.一项针对老年人腰痛的共病适应性运动计划（COMEBACK）的混合方法可行性研究：方案
Pilot Feasibility Stud. 2022 Jul 2;8(1):133. doi: 10.1186/s40814-022-01097-x.
6
The Necessity of Methodological Advances in Pain Research: Challenges and Opportunities.疼痛研究中方法学进展的必要性：挑战与机遇
Front Pain Res (Lausanne). 2021 May 26;2:634041. doi: 10.3389/fpain.2021.634041. eCollection 2021.
本文引用的文献
1
Symptom burden and clinical profile of COVID-19 deaths: a rapid systematic review and evidence summary.2019冠状病毒病死亡病例的症状负担与临床特征：一项快速系统综述及证据总结
BMJ Support Palliat Care. 2020 Dec;10(4):381-384. doi: 10.1136/bmjspcare-2020-002368. Epub 2020 May 28.
2
Novel Coronavirus Infection (COVID-19) in Humans: A Scoping Review and Meta-Analysis.人类新型冠状病毒感染（COVID-19）：一项范围综述与荟萃分析
J Clin Med. 2020 Mar 30;9(4):941. doi: 10.3390/jcm9040941.
3
Antinociceptive effect of intrathecal injection of miR-9-5p modified mouse bone marrow mesenchymal stem cells on a mouse model of bone cancer pain.鞘内注射 miR-9-5p 修饰的小鼠骨髓间充质干细胞对骨癌痛模型小鼠的镇痛作用。
J Neuroinflammation. 2020 Mar 16;17(1):85. doi: 10.1186/s12974-020-01765-w.
4
Injections of concentrated bone marrow aspirate as treatment for Discogenic pain: a retrospective analysis.浓缩骨髓抽吸注射治疗椎间盘源性疼痛：回顾性分析。
BMC Musculoskelet Disord. 2020 Feb 28;21(1):135. doi: 10.1186/s12891-020-3126-7.
5
P2X4 Receptors on Muscle Macrophages Are Required for Development of Hyperalgesia in an Animal Model of Activity-Induced Muscle Pain.肌纤维母细胞 P2X4 受体在活动诱发肌肉痛动物模型中痛觉过敏发展中的作用。
Mol Neurobiol. 2020 Apr;57(4):1917-1929. doi: 10.1007/s12035-019-01852-x. Epub 2020 Jan 2.
6
Intratendinous Injection of Mesenchymal Stem Cells for the Treatment of Rotator Cuff Disease: A 2-Year Follow-Up Study.肌腱内注射间充质干细胞治疗肩袖疾病：一项为期 2 年的随访研究。
Arthroscopy. 2020 Apr;36(4):971-980. doi: 10.1016/j.arthro.2019.11.120. Epub 2019 Dec 3.
7
Intra-articular injection of culture-expanded mesenchymal stem cells with or without addition of platelet-rich plasma is effective in decreasing pain and symptoms in knee osteoarthritis: a controlled, double-blind clinical trial.关节内注射培养扩增的间充质干细胞联合或不联合富血小板血浆治疗膝骨关节炎有效：一项对照、双盲临床试验。
Knee Surg Sports Traumatol Arthrosc. 2020 Jun;28(6):1989-1999. doi: 10.1007/s00167-019-05732-8. Epub 2019 Oct 5.
8
Cervical Muscle Tenderness in Temporomandibular Disorders and Its Associations with Diagnosis, Disease-Related Outcomes, and Comorbid Pain Conditions.颞下颌关节紊乱症中的颈部肌肉压痛及其与诊断、与疾病相关的结局和共患疼痛状况的关联。
J Oral Facial Pain Headache. 2020 Winter;34(1):67–76. doi: 10.11607/ofph.2374. Epub 2019 Aug 27.
9
TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes.TNFR2 促进 Treg 介导的神经病理性疼痛在两性中的恢复。
Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):17045-17050. doi: 10.1073/pnas.1902091116. Epub 2019 Aug 7.
10
Stem Cell Therapies for Treatment of Discogenic Low Back Pain: a Comprehensive Review.干细胞疗法治疗椎间盘源性下腰痛：全面综述。
Curr Pain Headache Rep. 2019 Jul 29;23(9):65. doi: 10.1007/s11916-019-0804-y.
Zotero 插件