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自身免疫性神经病学:抗 NMDAR 脑炎和抗 MOG 相关疾病的同时发生,病例报告。

Autoimmune neurology: Co-occurrence of anti-NMDAR encephalitis and anti-MOG associated disease, report of a case.

机构信息

Basic Research Center in Dementia and Central Neurvous System Demyelinating Diseases, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Neurosonología, Clínica Delgado, Lima, Peru.

Basic Research Center in Dementia and Central Neurvous System Demyelinating Diseases, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.

出版信息

J Neuroimmunol. 2021 Sep 15;358:577663. doi: 10.1016/j.jneuroim.2021.577663. Epub 2021 Jul 18.

Abstract

We report the case of a patient with symptoms of anti-NMDAR encephalitis and anti-MOG associated disease simultaneously, in whom the identification of antibodies guided to a more aggressive treatment strategy, resulting in a good clinical outcome. MRI is an important tool to diagnose this kind of patients. The co-occurrence of both diseases in infrequent, but atypical symptoms should increase our awareness of the possibility of an overlap syndrome.

摘要

我们报告了一例同时出现抗 NMDAR 脑炎和抗 MOG 相关疾病症状的患者,其抗体的鉴定指导了更积极的治疗策略,从而获得了良好的临床结局。MRI 是诊断这类患者的重要工具。这两种疾病同时发生的情况较为罕见,但不典型症状应提高我们对重叠综合征可能性的认识。

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