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在 中，铁供应对磷酸盐缺乏诱导的代谢变化的调节。

Modulation of Phosphate Deficiency-Induced Metabolic Changes by Iron Availability in .

机构信息

Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle, Germany.

Synergy Research Group Bioinformatics & Scientific Data, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle, Germany.

出版信息

Int J Mol Sci. 2021 Jul 16;22(14):7609. doi: 10.3390/ijms22147609.

DOI:10.3390/ijms22147609
PMID:34299231
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8306678/
Abstract

Concurrent suboptimal supply of several nutrients requires the coordination of nutrient-specific transcriptional, phenotypic, and metabolic changes in plants in order to optimize growth and development in most agricultural and natural ecosystems. Phosphate (P) and iron (Fe) deficiency induce overlapping but mostly opposing transcriptional and root growth responses in . On the metabolite level, P deficiency negatively modulates Fe deficiency-induced coumarin accumulation, which is controlled by Fe as well as P deficiency response regulators. Here, we report the impact of Fe availability on seedling growth under P limiting conditions and on P deficiency-induced accumulation of amino acids and organic acids, which play important roles in P use efficiency. Fe deficiency in P replete conditions hardly changed growth and metabolite profiles in roots and shoots of , but partially rescued growth under conditions of P starvation and severely modulated P deficiency-induced metabolic adjustments. Analysis of T-DNA insertion lines revealed the concerted coordination of metabolic profiles by regulators of Fe (FIT, bHLH104, BRUTUS, PYE) as well as of P (SPX1, PHR1, PHL1, bHLH32) starvation responses. The results show the interdependency of P and Fe availability and the interplay between P and Fe starvation signaling on the generation of plant metabolite profiles.

摘要

同时存在几种营养物供应不足的情况时，植物需要协调特定营养物的转录、表型和代谢变化，以优化其在大多数农业和自然生态系统中的生长和发育。在拟南芥中，磷（P）和铁（Fe）缺乏会引起重叠但大多相反的转录和根生长反应。在代谢物水平上，P 缺乏会负调控由 Fe 以及 P 缺乏响应调节剂控制的香豆素积累。在这里，我们报告了 Fe 供应对 P 限制条件下幼苗生长以及对 P 缺乏诱导的氨基酸和有机酸积累的影响，这些物质在 P 利用效率中起着重要作用。在 P 充足条件下的 Fe 缺乏几乎不会改变拟南芥根和地上部分的生长和代谢物图谱，但在 P 饥饿条件下部分挽救了生长，并严重调节了 P 缺乏诱导的代谢调整。对 T-DNA 插入系的分析表明，Fe（FIT、bHLH104、BRUTUS、PYE）以及 P（SPX1、PHR1、PHL1、bHLH32）饥饿响应的调节剂协同协调了代谢图谱。研究结果表明 P 和 Fe 有效性的相互依赖性以及 P 和 Fe 饥饿信号之间的相互作用在植物代谢物图谱的产生中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a81/8306678/1453a4941443/ijms-22-07609-g008.jpg
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