Solid State Chemistry Department, Institut de Ciencia de Materials de Barcelona, CSIC, Campus UAB, 08193 Bellaterra, Spain.
Molecules. 2021 Jul 12;26(14):4236. doi: 10.3390/molecules26144236.
Nanostructuring nanocarbons with IrO yields to material coatings with large charge capacities for neural electrostimulation, and large reproducibility in time, that carbons do not exhibit. This work shows the contributions of carbon and the different nanostructures present, as well as the impact of functionalizing graphene with oxygen and nitrogen, and the effects of including conducting polymers within the hybrid materials. Different mammalian neural growth models differentiate the roles of the substrate material in absence and in presence of applied electric fields and address optimal electrodes for the future clinical applications.
用铱氧化物对纳米碳进行纳米结构化处理，得到了具有大充电容量的神经电刺激材料涂层，而且其重复性也比碳材料要好。这项工作展示了碳和不同纳米结构的贡献，以及用氧和氮对石墨烯进行功能化的影响，以及在混合材料中包含导电聚合物的影响。不同的哺乳动物神经生长模型区分了在没有和存在外加电场的情况下基底材料的作用，并为未来的临床应用确定了最佳电极。
