From the Department of Neuroradiology, Mayo Clinic, Rochester, Minnesota
From the Department of Neuroradiology, Mayo Clinic, Rochester, Minnesota.
AJNR Am J Neuroradiol. 2021 Sep;42(9):1558-1565. doi: 10.3174/ajnr.A7249. Epub 2021 Jul 22.
In recent years, there has been substantial progression in the field of stroke clot/thrombus imaging. Thrombus imaging aims to deduce the histologic composition of the clot through evaluation of various imaging characteristics. If the histology of a thrombus can be reliably determined by noninvasive imaging methods, critical information may be extrapolated about its expected response to treatment and about the patient's clinical outcome. Crucially, as we move into an era of stroke therapy individualization, determination of the histologic composition of a clot may be able to guide precise and targeted therapeutic effort. Most radiologists, however, remain largely unfamiliar with the topic of clot imaging. This article will review the current literature regarding clot imaging, including its histologic backdrop, the correlation of images with cellular components and treatment responsiveness, and future expectations.
近年来，中风血栓/栓子成像领域取得了重大进展。血栓成像旨在通过评估各种成像特征来推断血栓的组织学成分。如果血栓的组织学可以通过非侵入性成像方法可靠地确定，那么就可以推断出关于其对治疗的预期反应以及患者临床结果的关键信息。至关重要的是，随着我们进入个体化卒中治疗的时代，确定血栓的组织学成分可能能够指导精确和有针对性的治疗努力。然而，大多数放射科医生对血栓成像这个主题仍然知之甚少。本文将回顾关于血栓成像的当前文献，包括其组织学背景、图像与细胞成分和治疗反应的相关性以及未来的预期。
