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发育异常:一个真实的概念还是一个不恰当的名称?

Dysplasia. A real concept or a misnomer?

作者信息

Koss L G

出版信息

Obstet Gynecol. 1978 Mar;51(3):374-9.

PMID:343018
Abstract

The purpose of this paper is to summarize the author's views on precancerous lesions of the epithelium of the uterine cervix. It is pointed out that the pathologist's ability to prognosticate the outcome of any such lesion is limited. The names attached to these lesions, ranging from mild dysplasia to carcinoma in situ do not necessarily reflect their true biologic potential in terms of disappearance, persistence, or progression. It is suggested that a unified nomenclature of these lesions may be helpful in clarifying the issue at hand. Comments on the accomplishments and failures of the cytologic methods of diagnosis of these lesions are appended.

摘要

本文旨在总结作者对子宫颈上皮癌前病变的观点。文中指出,病理学家预测任何此类病变结果的能力是有限的。这些病变的命名,从轻度发育异常到原位癌,就其消失、持续或进展而言,不一定能反映其真正的生物学潜能。有人提出,对这些病变采用统一的命名法可能有助于澄清当前的问题。文末还附上了对这些病变细胞学诊断方法的成就与不足的评论。

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