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酒精控制政策加剧了年轻人全因死亡率的长期趋势。

Alcohol control policies add to secular trends in all-cause mortality rates in young adults.

机构信息

Institute for Mental Health Policy Research, Centre for Addiction and Mental Health (CAMH), 33 Russell Street, Toronto, ON, M5S 2S1, Canada.

Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Chemnitzer Str. 46, 01187, Dresden, Germany.

出版信息

Sci Rep. 2021 Jul 23;11(1):15127. doi: 10.1038/s41598-021-94562-1.

DOI:10.1038/s41598-021-94562-1
PMID:34302018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8302690/
Abstract

Alcohol consumption is a major risk factor for premature mortality. Although alcohol control policies are known to impact all-cause mortality rates, the effect that policies have on specific age groups is an important area of research. This study investigates the effect of alcohol control policies implemented in 2009 and 2017 in Lithuania on all-cause mortality rates. All-cause mortality rates (deaths per 100,000 people) were obtained for 2001-2018 by 10-year age groups (20-29, 30-39, 40-49 years, etc.). All-cause mortality rates, independent of macro-level secular trends (e.g., economic trends) were examined. Following a joinpoint analysis to control for secular trends, an interrupted time series analysis showed that alcohol control policies had a significant effect on all-cause mortality rates (p = .018), with the most significant impact occurring among young adults (20-29 and 30-39 years of age). For these age groups, their mortality rate decreased during the 12 months following policy implementation (following the policy in 2009 for those 20-29 years of age, p = .0026, and following the policy in 2017 for those 30-39 years of age, p = .011). The results indicate that alcohol control policy can impact all-cause mortality rates, above and beyond secular trends, and that the impact is significant among young adults.

摘要

饮酒是导致早逝的主要危险因素之一。尽管控制酒精的政策已知会影响全因死亡率,但政策对特定年龄组的影响是一个重要的研究领域。本研究调查了 2009 年和 2017 年在立陶宛实施的酒精控制政策对全因死亡率的影响。通过 10 年年龄组(20-29、30-39、40-49 岁等)获得了 2001-2018 年的全因死亡率(每 10 万人死亡人数)。研究了不受宏观长期趋势(例如经济趋势)影响的全因死亡率。在进行了联合分析以控制长期趋势之后,中断时间序列分析表明,酒精控制政策对全因死亡率有显著影响(p=0.018),对年轻人(20-29 岁和 30-39 岁)的影响最大。对于这些年龄组,在政策实施后的 12 个月内,其死亡率下降(对于 20-29 岁的人群,在 2009 年实施政策后,p=0.0026,对于 30-39 岁的人群,在 2017 年实施政策后,p=0.011)。结果表明,酒精控制政策可以影响全因死亡率,超出长期趋势的影响,并且对年轻人的影响显著。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5049/8302690/9001e8db967c/41598_2021_94562_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5049/8302690/d095dbcda75d/41598_2021_94562_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5049/8302690/9001e8db967c/41598_2021_94562_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5049/8302690/d095dbcda75d/41598_2021_94562_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5049/8302690/9001e8db967c/41598_2021_94562_Fig2_HTML.jpg

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