Štelemėkas Mindaugas, Manthey Jakob, Badaras Robertas, Casswell Sally, Ferreira-Borges Carina, Kalėdienė Ramunė, Lange Shannon, Neufeld Maria, Petkevičienė Janina, Radišauskas Ričardas, Room Robin, Telksnys Tadas, Zurlytė Ingrida, Rehm Jürgen
Health Research Institute, Faculty of Public Health, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Department of Preventive Medicine, Faculty of Public Health, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Addiction. 2021 Oct;116(10):2673-2684. doi: 10.1111/add.15470. Epub 2021 Apr 6.
Alcohol use has been identified as a major risk factor for burden of mortality and disease, particularly for countries in eastern Europe. During the past two decades, several countries in this region have implemented effective alcohol policy measures to combat this burden. The aim of the current study was to measure the association between Lithuania's alcohol control policies and adult all-cause mortality.
Interrupted time-series methodology by means of general additive models.
Lithuania.
Adult population of Lithuania, aged 20 years and older.
Alcohol control policies were ascertained via a document review of relevant legislation materials. Policy effects were evaluated as follows: (1) slope changes in periods of legislative (non-)activity with regard to alcohol control policy (analysis 1); (2) level changes of three interventions following recommendations of the World Health Organization (analysis 2); and (3) level changes of seven interventions judged a priori by an international panel of experts (analysis 3). Mortality was measured by sex-stratified and total monthly age-standardized rates of all-cause mortality for the adult population.
During the period 2001-18, effective alcohol control policy measures were implemented on several occasions, and in those years the all-cause mortality rate declined by approximately 3.2% more than in years without such policies. In particular, the implementation of increased taxation in 2017 was associated with reduced mortality over and above the general trend for men and in total for all analyses, which amounted to 1452 deaths avoided (95% confidence interval = -166 to -2739) in the year following the implementation of the policy.
Alcohol control policies in Lithuania appear to have reduced the overall adult all-cause mortality over and above secular trends.
饮酒已被确定为导致死亡和疾病负担的主要风险因素，尤其是在东欧国家。在过去二十年中，该地区的几个国家已实施有效的酒精政策措施来应对这一负担。本研究的目的是衡量立陶宛的酒精控制政策与成人全因死亡率之间的关联。
采用广义相加模型的中断时间序列方法。
立陶宛。
立陶宛20岁及以上的成年人口。
通过对相关立法材料的文献回顾确定酒精控制政策。政策效果评估如下：（1）酒精控制政策立法（非）活动期间的斜率变化（分析1）；（2）根据世界卫生组织的建议进行的三项干预措施的水平变化（分析2）；（3）由国际专家小组预先判定的七项干预措施的水平变化（分析3）。死亡率通过按性别分层的成人全因死亡率月度年龄标准化率和总率来衡量。
在2001年至2018年期间，多次实施了有效的酒精控制政策措施，在这些年份中，全因死亡率比没有此类政策的年份下降了约3.2%。特别是，2017年提高税收的实施与男性死亡率下降以及所有分析中的总体死亡率下降相关，在政策实施后的一年中，这相当于避免了1452例死亡（95%置信区间=-166至-2739）。
立陶宛的酒精控制政策似乎在长期趋势之外降低了总体成人全因死亡率。
