Niederer W, Eltz H
Ophthalmologica. 1978;176(1):45-51. doi: 10.1159/000308690.
Corneal transplantations were performed on both eyes of 19 albino rabbits. For each animal both grafts were taken from one pigmented donor rabbit. In all animals one eye was treated with a 2% 5alpha-androstane-3,17-dione ointment (alphaA) and the other eye with an ointment containing no steroid (6 rabbits) or 2% cortisol (13 rabbits). Our experiments showed that alphaA cannot inhibit the efferent limb of corneal graft rejection as effectively as cortisol. we discuss some histological features of corneal graft rejection and our technique of corneal grafting in rabbits.
对19只白化兔的双眼进行了角膜移植。每只动物的两片移植物均取自一只有色供体兔。在所有动物中，一只眼睛用2%的5α-雄甾烷-3,17-二酮软膏（αA）治疗，另一只眼睛用不含类固醇的软膏（6只兔）或2%的皮质醇软膏（13只兔）治疗。我们的实验表明，αA抑制角膜移植排斥反应传出支的效果不如皮质醇。我们讨论了角膜移植排斥反应的一些组织学特征以及我们在兔角膜移植中的技术。
