Mannis M J, Krachmer J H
Invest Ophthalmol Vis Sci. 1981 Mar;20(3):382-6.
Penetrating corneal homografts were performed in albino rabbits. The experimental group received grafts soaked in a solution of concanavalin A; the control group received grafts soaked in lactated Ringer's solution. Animals with technically successful grafts were subsequently exposed to an additional antigenic stimulus from the corneal donor via skin grafting. This procedure produces a uniformly high rate of corneal graft rejection. The two groups were compared for the frequency and onset of the graft reaction. Results demonstrated no difference between control and experimental groups. The significance of these findings is discussed.
在白化兔身上进行穿透性角膜同种移植。实验组接受浸泡在伴刀豆球蛋白A溶液中的移植物；对照组接受浸泡在乳酸林格氏液中的移植物。移植技术成功的动物随后通过皮肤移植接触来自角膜供体的额外抗原刺激。该程序会产生一致的高角膜移植排斥率。比较两组移植反应的频率和发作情况。结果表明对照组和实验组之间没有差异。讨论了这些发现的意义。
