He Yujiao, Yang Lihui
Department of Otolaryngology，Liaoning Provincial People's Hospital，Shenyang，110000，China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Jun;35(6):535-537;542. doi: 10.13201/j.issn.2096-7993.2021.06.011.
To study the value of auditory brainstem response（ABR） and 40 Hz auditory evoked potential（40Hz AERP） in adult patients with sudden deafness. Pure tone audiometry, ABR and 40 Hz AERP were performed in 184 adult patients with sudden deafness before treatment. According to the frequency and severity of hearing loss revealed by pure tone audiometry, the patients were divided into low-frequency decline type（86 cases）, high-frequency decline type（60 cases）, flat type（32 cases） and total deafness type（6 cases, statistical analysis were not conducted in this group due to the incomplete elicitation of reaction threshold）. Data from 178 ears were collected for statistical results. After treatment, pure tone audiometry, ABR and 40 Hz AERP were performed. As for ABR threshold, its correlation with 500 Hz threshold of subjective pure tone test was poor（=0.233, =0.706）, and was worse with 1000 Hz threshold（=0.472, =0.345）. ABR threshold was closely correlated with 2000 Hz threshold（=0.878, =0.021） and 4000 Hz threshold（=0.800, =0.010） of subjective pure tone test. As for 40 Hz AERP threshold, its correlation with 500 Hz threshold of subjective pure tone audiometry was good（=0.992, =0）, and was better with 1000 Hz threshold（=0.912, =0.110）. 40 Hz AERP threshold was poorly correlated with 2000 Hz threshold（=0.210, =0.690） and 4000 Hz threshold（=0.370, =0.945） of subjective pure tone audiometry. ABR and subjective pure tone audiometry have high correlation at high frequency, while 40 Hz AERP and subjective pure tone audiometry have high correlation at low frequency. ABR and 40 Hz AERP can comprehensively reflect the severity of hearing loss in adult patients with sudden deafness.
研究听性脑干反应（ABR）和40赫兹听觉诱发电位（40Hz AERP）在成年突发性聋患者中的应用价值。对184例成年突发性聋患者治疗前进行纯音听力测试、ABR及40Hz AERP检测。根据纯音听力测试显示的听力损失频率及程度，将患者分为低频下降型（86例）、高频下降型（60例）、平坦型（32例）和全聋型（6例，该组因反应阈值引出不全未进行统计分析）。收集178耳数据进行统计分析。治疗后再次进行纯音听力测试、ABR及40Hz AERP检测。ABR阈值与主观纯音测试500Hz阈值的相关性较差（r=0.233，P=0.706），与1000Hz阈值的相关性更差（r=0.472，P=0.345）。ABR阈值与主观纯音测试2000Hz阈值（r=0.878，P=0.021）及4000Hz阈值（r=0.800，P=0.010）密切相关。40Hz AERP阈值与主观纯音听力测试500Hz阈值的相关性良好（r=0.992，P=0），与1000Hz阈值的相关性较好（r=0.912，P=0.110）。40Hz AERP阈值与主观纯音听力测试2000Hz阈值（r=0.210，P=0.690）及4000Hz阈值（r=0.370，P=0.945）的相关性较差。ABR与主观纯音听力测试在高频具有较高相关性，而40Hz AERP与主观纯音听力测试在低频具有较高相关性。ABR和40Hz AERP能综合反映成年突发性聋患者听力损失的严重程度。
