Quispe Miguel Angel, Valenzuela José Alberto Pacheco, Cruz Alex Rubén Huamán de la, Silva Clara Raquel Espinoza, Quiñonez Greta Hinostroza, Cervantes Galia Mavel Manyari
Universidad Nacional del Centro del Perú, El Tambo - Huancayo, Perú.
Facultad de Ingeniería en Industrias Alimentarias, Universidad Nacional del Centro del Perú, El Tambo - Huancayo, Perú.
Acta Sci Pol Technol Aliment. 2021 Jul-Sep;20(3):277-290. doi: 10.17306/J.AFS.0937.
The globe artichoke (Cynara scolymus L.) is a rich source of phenolic compounds which may be extracted by ultrasound technology and used as a medicinal alternative. The objective of this work was to determine the radiation amplitude (%), ethanol concentration (%), and time extraction (min) required to guarantee an elevated content of polyphenol compounds.
The optimal extraction conditions were assessed through the Box-Wilson design and by applying Composite Face Centered (CCFC) and total phenolic compounds (TPC) as the response variables.
A quadratic model was adequate, with R2 = 0.993. The optimal conditions were a radiation amplitude of 97%, an ethanol concentration of 53%, and an extraction time of 9.7 min. The optimized extract of artichoke bracts (Cynara scolymus L.) showed a TPC of 25.13 (±0.030) mg GAE/g, an antioxidant activity DPPH of 39.79 (±0.014) mmol Trolox equivalents (TE), and an antioxidant capacity TEAC of 33.98 (±0.03) mmol Trolox equivalents.
The results showed values closely related to the expected values, indicating that the models were well-developed.
洋蓟（Cynara scolymus L.）是酚类化合物的丰富来源，可通过超声技术提取并用作药用替代品。本研究的目的是确定保证多酚化合物含量升高所需的辐射幅度（%）、乙醇浓度（%）和提取时间（分钟）。
通过Box-Wilson设计并应用复合中心复合设计（CCFC）和总酚化合物（TPC）作为响应变量来评估最佳提取条件。
二次模型适用，R2 = 0.993。最佳条件为辐射幅度97%、乙醇浓度53%和提取时间9.7分钟。优化后的洋蓟苞片（Cynara scolymus L.）提取物的总酚含量为25.13（±0.030）mg GAE/g，抗氧化活性DPPH为39.79（±0.014）mmol Trolox当量（TE），抗氧化能力TEAC为33.98（±0.03）mmol Trolox当量。
结果显示的值与预期值密切相关，表明模型构建良好。
