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[无可用内容]。

[Not Available].

作者信息

Krueger Robert F, Kotov Roman, Watson David, Forbes Miriam K, Eaton Nicholas R, Ruggero Camilo J, Simms Leonard J, Widiger Thomas A, Achenbach Thomas M, Bach Bo, Bagby R Michael, Bornovalova Marina A, Carpenter William T, Chmielewski Michael, Cicero David C, Clark Lee Anna, Conway Christopher, DeClercq Barbara, DeYoung Colin G, Docherty Anna R, Drislane Laura E, First Michael B, Forbush Kelsie T, Hallquist Michael, Haltigan John D, Hopwood Christopher J, Ivanova Masha Y, Jonas Katherine G, Latzman Robert D, Markon Kristian E, Miller Joshua D, Morey Leslie C, Mullins-Sweatt Stephanie N, Ormel Johan, Patalay Praveetha, Patrick Christopher J, Pincus Aaron L, Regier Darrel A, Reininghaus Ulrich, Rescorla Leslie A, Samuel Douglas B, Sellbom Martin, Shackman Alexander J, Skodol Andrew, Slade Tim, South Susan C, Sunderland Matthew, Tackett Jennifer L, Venables Noah C, Waldman Irwin D, Waszczuk Monika A, Waugh Mark H, Wright Aidan G C, Zald David H, Zimmermann Johannes

机构信息

Department of Psychology, University of Minnesota, Minneapolis, MN, USA.

Department of Psychiatry, Stony Brook University, Stony Brook, NY, USA.

出版信息

Ann Med Psychol (Paris). 2021 Jan;179(1):95-106. doi: 10.1016/j.amp.2020.11.015. Epub 2021 Jan 8.

DOI:10.1016/j.amp.2020.11.015
PMID:34305151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8309948/
Abstract

Shortcomings of approaches to classifying psychopathology based on expert consensus have given rise to contemporary efforts to classify psychopathology quantitatively. In this paper, we review progress in achieving a quantitative and empirical classification of psychopathology. A substantial empirical literature indicates that psychopathology is generally more dimensional than categorical. When the discreteness versus continuity of psychopathology is treated as a research question, as opposed to being decided as a matter of tradition, the evidence clearly supports the hypothesis of continuity. In addition, a related body of literature shows how psychopathology dimensions can be arranged in a hierarchy, ranging from very broad "spectrum level" dimensions, to specific and narrow clusters of symptoms. In this way, a quantitative approach solves the "problem of comorbidity" by explicitly modeling patterns of co-occurrence among signs and symptoms within a detailed and variegated hierarchy of dimensional concepts with direct clinical utility. Indeed, extensive evidence pertaining to the dimensional and hierarchical structure of psychopathology has led to the formation of the Hierarchical Taxonomy of Psychopathology (HiTOP) Consortium. This is a group of 70 investigators working together to study empirical classification of psychopathology. In this paper, we describe the aims and current foci of the HiTOP Consortium. These aims pertain to continued research on the empirical organization of psychopathology; the connection between personality and psychopathology; the utility of empirically based psychopathology constructs in both research and the clinic; and the development of novel and comprehensive models and corresponding assessment instruments for psychopathology constructs derived from an empirical approach.

摘要

基于专家共识对精神病理学进行分类的方法存在缺陷,这引发了当代对精神病理学进行定量分类的努力。在本文中,我们回顾了在实现精神病理学定量和实证分类方面取得的进展。大量实证文献表明,精神病理学总体上更具维度性而非类别性。当将精神病理学的离散性与连续性作为一个研究问题来对待,而不是按照传统来决定时,证据明显支持连续性假说。此外,相关文献表明精神病理学维度如何能够排列成一个层次结构,从非常宽泛的“光谱水平”维度到具体且狭窄的症状群。通过这种方式,定量方法通过在具有直接临床效用的详细且多样的维度概念层次结构中明确建模症状和体征的共现模式,解决了“共病问题”。事实上,与精神病理学维度和层次结构相关的大量证据导致了精神病理学层次分类法(HiTOP)联盟的形成。这是一个由70名研究人员组成的团队,他们共同致力于研究精神病理学的实证分类。在本文中,我们描述了HiTOP联盟的目标和当前重点。这些目标涉及对精神病理学实证组织的持续研究;人格与精神病理学之间的联系;基于实证的精神病理学结构在研究和临床中的效用;以及为源自实证方法的精神病理学结构开发新颖且全面的模型和相应评估工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb59/8309948/a4f71e8cd5c9/nihms-1721484-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb59/8309948/1d69fa230c3c/nihms-1721484-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb59/8309948/ad92778fbb80/nihms-1721484-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb59/8309948/a4f71e8cd5c9/nihms-1721484-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb59/8309948/1d69fa230c3c/nihms-1721484-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb59/8309948/ad92778fbb80/nihms-1721484-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb59/8309948/a4f71e8cd5c9/nihms-1721484-f0003.jpg

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本文引用的文献

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Accurate Genomic Prediction of Human Height.人类身高的精确基因组预测。
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2
The time has come for dimensional personality disorder diagnosis.进行维度性人格障碍诊断的时候到了。
Personal Ment Health. 2018 Feb;12(1):82-86. doi: 10.1002/pmh.1408. Epub 2017 Dec 11.
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Three Approaches to Understanding and Classifying Mental Disorder: ICD-11, DSM-5, and the National Institute of Mental Health's Research Domain Criteria (RDoC).理解和分类精神障碍的三种方法:ICD-11、DSM-5 和国家精神卫生研究所的研究领域标准 (RDoC)。
Psychol Sci Public Interest. 2017 Sep;18(2):72-145. doi: 10.1177/1529100617727266.
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The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders Compared With Diagnosis-Specific Protocols for Anxiety Disorders: A Randomized Clinical Trial.与焦虑症特定诊断方案相比,情绪障碍跨诊断治疗统一方案的随机临床试验。
JAMA Psychiatry. 2017 Sep 1;74(9):875-884. doi: 10.1001/jamapsychiatry.2017.2164.
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Psychoneurometric assessment of dispositional liabilities for suicidal behavior: phenotypic and etiological associations.精神神经计量学评估自杀行为的性格倾向:表型和病因学关联。
Psychol Med. 2018 Feb;48(3):463-472. doi: 10.1017/S0033291717001830. Epub 2017 Jul 17.
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The slow death of the concept of schizophrenia and the painful birth of the psychosis spectrum.精神分裂症概念的缓慢消亡与精神病谱系的痛苦诞生。
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Delineating the joint hierarchical structure of clinical and personality disorders in an outpatient psychiatric sample.在一个门诊精神科样本中描绘临床和人格障碍的联合层次结构。
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What do clinicians treat: Diagnoses or symptoms? The incremental validity of a symptom-based, dimensional characterization of emotional disorders in predicting medication prescription patterns.临床医生治疗的是:诊断还是症状?基于症状的、情绪障碍维度特征对预测药物处方模式的增量有效性。
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