Vijayaraghavalu Shashikanth, Prasad R Guru, Rajkumar Sathish
General Surgery, ACS Medical College Hospital, Chennai, IND.
General Surgery/Surgical Oncology, ACS Medical College Hospital, Chennai, IND.
Cureus. 2021 Jun 13;13(6):e15630. doi: 10.7759/cureus.15630. eCollection 2021 Jun.
Background Hemorrhoids are a common condition that presents with bleeding per rectum, pain at rest and defecation, mucosal discharge, and prolapse. Surgical hemorrhoidectomy is the treatment method of choice for Grade 3 and Grade 4 hemorrhoids. Hemorrhoidectomy is associated with postoperative pain and no single surgical technique has been proved to significantly reduce the pain. We analyzed in our study the effect of lateral internal sphincterotomy with hemorrhoidectomy on postoperative pain, anorectal function, and retention of urine after the Milligan and Morgan technique. Methods This randomized, prospective, and comparative study included 200 Grade 3 and Grade 4 hemorrhoids patients who were scheduled for surgical management. The patients were classified randomly into two groups with an equal number of participants: Group A underwent Milligan & Morgan open hemorrhoidectomy and Group B underwent lateral internal sphincterotomy (LIS) in addition to Milligan and Morgan open hemorrhoidectomy. Postoperative pain was recorded using the Visual Analog Scale (VAS) score for up to 48 hours. Postoperative bleeding, urinary retention, and bowel and gas incontinence were noted. Long-term follow-up at six and 24 months for anal stenosis, anal fissure, incontinence, and recurrence was also noted. Results Patients who underwent LIS showed a significant reduction in postoperative pain at 12 hours (p=0.0008*), 24 hours (p=0.000*), and 48 hours (p=0.003*); the time taken to request rescue analgesia was similar between the two groups (p=0.07). Side effects, such as postoperative bleeding and urinary retention, were significantly lower after LIS (p=0.001* and p=0.01*, respectively), and gas incontinence was significantly higher after LIS (p=0.002*). The long-term outcomes of anal fissure were significantly higher without LIS at six months (p=0.02*) and 24 months (p=0.04*) and those of anal stenosis were significantly higher without LIS at six months (p=0.04*). Conclusions From our study, we conclude that postoperative pain, bleeding, and urinary retention were significantly lower after LIS, and gas incontinence was transient. The long-term outcomes, which included anal stenosis and anal fissure, were significantly lower after LIS. However, bowel and gas incontinence and recurrence were not altered. Therefore, we conclude that the addition of LIS to hemorrhoidectomy improves patient outcomes in terms of postoperative pain and anorectal function.
痔疮是一种常见病症,表现为直肠出血、静息及排便时疼痛、黏膜分泌物及脱垂。手术痔切除术是3级和4级痔疮的首选治疗方法。痔切除术与术后疼痛相关,且尚无单一手术技术被证明能显著减轻疼痛。我们在研究中分析了痔切除术联合外侧内括约肌切开术对采用Milligan和Morgan技术术后疼痛、肛门直肠功能及尿潴留的影响。
这项随机、前瞻性对照研究纳入了200例计划接受手术治疗的3级和4级痔疮患者。患者被随机分为两组,每组人数相等:A组接受Milligan & Morgan开放式痔切除术,B组在Milligan和Morgan开放式痔切除术基础上接受外侧内括约肌切开术(LIS)。使用视觉模拟量表(VAS)评分记录术后长达48小时的疼痛情况。记录术后出血、尿潴留、大便及气体失禁情况。还对术后6个月和24个月的肛门狭窄、肛裂、失禁及复发情况进行长期随访。
接受LIS的患者在术后12小时(p = 0.0008*)、24小时(p = 0.000*)和48小时(p = 0.003*)的疼痛显著减轻;两组请求急救镇痛的时间相似(p = 0.07)。LIS术后的副作用,如术后出血和尿潴留,显著更低(分别为p = 0.001和p = 0.01),而LIS术后气体失禁显著更高(p = 0.002*)。无LIS组术后6个月(p = 0.02*)和24个月(p = 0.04*)肛裂的长期发生率显著更高,无LIS组术后6个月肛门狭窄的长期发生率显著更高(p = 0.04*)。
从我们的研究中得出,LIS术后的术后疼痛、出血和尿潴留显著更低,且气体失禁是短暂的。LIS术后包括肛门狭窄和肛裂在内的长期结果显著更低。然而,大便及气体失禁和复发情况未改变。因此,我们得出结论,痔切除术联合LIS在术后疼痛和肛门直肠功能方面改善了患者预后。