Ogura H, Kubota H, Murakami N, Tomoda T, Hamada F, Matsumoto K, Araki K, Ogura Y, Kurashige T, Kitamura I
Department of Pediatrics, Kochi Medical School.
Jpn J Antibiot. 1987 Aug;40(8):1496-501.
A new oxacephem antibiotic, flomoxef sodium (FMOX, 6315-S), was studied for its clinical efficacy in the field of pediatrics. The treated patients were infants and children ranging from 6 months to 14 years old suffering from bacterial pneumonia in 3 cases, acute tonsillitis in 2 cases, acute enterocolitis in 2 cases, and cellulitis and urinary tract infection in 1 case each, a total of 9 cases. FMOX was administered at (levels of) 57-150 mg/kg in daily dose with durations of treatment ranging from 5 to 18 days. Clinical efficacies of good or excellent results were obtained in all cases (excellent in 4, good in 5). As an adverse reaction, eosinophilia was observed in 1 patient. This elevation is, however, normalized with the cessation of the treatment.
一种新的氧头孢烯类抗生素氟氧头孢钠（FMOX，6315 - S）在儿科领域的临床疗效进行了研究。治疗的患者为6个月至14岁的婴幼儿和儿童，其中细菌性肺炎3例，急性扁桃体炎2例，急性小肠结肠炎2例，蜂窝织炎和尿路感染各1例，共9例。氟氧头孢钠的日剂量为57 - 150mg/kg，治疗时间为5至18天。所有病例均获得良好或优异的临床疗效（优异4例，良好5例）。作为不良反应，1例患者出现嗜酸性粒细胞增多。然而，随着治疗的停止，这种升高恢复正常。
