Fuwa N, Morita K, Okumura E, Ito Y
Dept. of Radiotherapy, Aichi Cancer Center Hospital.
Gan No Rinsho. 1987 Dec;33(15):1867-74.
From 1965 through 1985, 85 patients with carcinoma of the nasopharynx were irradiated with curative intent at the Department of Radiation Therapy, Aichi Cancer Center Hospital. The observed 5-year survival rate was found to be 34%. Local recurrence was observed in 15 cases, regional lymph node recurrence in 10 cases, local and regional lymph node recurrence in 2 cases and distant metastases in 24 cases. Most manifestations of recurrence appeared within 2 years after treatment. Local recurrence was often observed in the base of skull in patients in advanced stages of their disease (T 3-4). The likelihood of a distant metastasis was stronger in patients with a bilateral neck nodes metastases and/or a lower neck metastases.
1965年至1985年期间,爱知癌症中心医院放射治疗科对85例鼻咽癌患者进行了根治性放疗。观察到的5年生存率为34%。15例出现局部复发,10例出现区域淋巴结复发,2例出现局部和区域淋巴结复发,24例出现远处转移。大多数复发表现出现在治疗后2年内。疾病晚期(T3 - 4)患者的局部复发常发生在颅底。双侧颈部淋巴结转移和/或下颈部转移患者发生远处转移的可能性更大。