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识别适合肺段切除术的肺癌患者:简要综述

Identifying Lung Cancer Patients Suitable for Segmentectomy: A Brief Review.

作者信息

Wang Chunguo, Wu Sikai, Zhang Rongwei, Jin Ke, Qian Yicheng, Mao Ning, Liu Yun, Zhang Miao, Zhang Ke, Wang Renfeng, Huang Gang, Zhang Min, Chen Baofu, Shen Jianfei

机构信息

Key Laboratory of Minimally Invasive Techniques & Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Linhai, China.

Department of Thoracic Surgery, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, China.

出版信息

Front Surg. 2021 Jul 8;8:637441. doi: 10.3389/fsurg.2021.637441. eCollection 2021.

DOI:10.3389/fsurg.2021.637441
PMID:34307441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8295684/
Abstract

In 1995, a clinical randomized controlled study (RCT) conducted by the Lung Cancer Study Group (LCSG) pointed out that the lobectomy was the gold standard for treating early lung cancer. However, with the development of technology, the results of several retrospective studies have shown that the efficacy of pulmonary segmentectomy is equivalent to that of lobectomy. Currently, it is still controversial whether segmental resection or lobectomy should be performed for early lung cancer. Thus, we aim to summarize the indications of segmentectomy. To conduct the review, previous researches involving indications of segmentectomy were collected from the literature using Pubmed. These articles were published and accepted in English in the medical literature from 2013 to 2020. We have focused on segmentectomy and its indications. A total of 176 articles were retrieved from the Pubmed database, of which 31 articles included indications for segmentectomy. We summarized the relevant content, and the potential and prospect of segmentectomy for the treatment of lung cancer were emphasized. These findings have a number of important implications for future practice. Pulmonary segmentectomy is a very vital surgical procedure for select patients with lung cancer, which provides a novel approach for the treatment of lung cancer and the survival of lung cancer patients.

摘要

1995年,肺癌研究组(LCSG)进行的一项临床随机对照研究(RCT)指出,肺叶切除术是治疗早期肺癌的金标准。然而,随着技术的发展,多项回顾性研究结果表明,肺段切除术的疗效与肺叶切除术相当。目前,早期肺癌应行肺段切除术还是肺叶切除术仍存在争议。因此,我们旨在总结肺段切除术的适应证。为进行本综述,我们通过Pubmed从文献中收集了此前涉及肺段切除术适应证的研究。这些文章于2013年至2020年期间在医学文献中以英文发表并被接受。我们重点关注肺段切除术及其适应证。从Pubmed数据库中共检索到176篇文章,其中31篇文章包含肺段切除术的适应证。我们总结了相关内容,并强调了肺段切除术治疗肺癌的潜力和前景。这些发现对未来的实践有许多重要意义。肺段切除术对于部分肺癌患者而言是一项非常重要的外科手术,它为肺癌治疗及肺癌患者的生存提供了一种新方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/8295684/1e0e0910f9c2/fsurg-08-637441-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/8295684/5855ab0d24cb/fsurg-08-637441-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/8295684/1e0e0910f9c2/fsurg-08-637441-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/8295684/5855ab0d24cb/fsurg-08-637441-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/8295684/1e0e0910f9c2/fsurg-08-637441-g0002.jpg

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本文引用的文献

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J Thorac Cardiovasc Surg. 2022 Jan;163(1):289-301.e2. doi: 10.1016/j.jtcvs.2020.09.146. Epub 2020 Nov 12.
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A multi-institutional randomized phase III trial comparing anatomical segmentectomy and wedge resection for clinical stage IA non-small cell lung cancer in high-risk operable patients: Japan Clinical Oncology Group Study JCOG1909 (ANSWER study).一项多机构、随机、III 期临床试验,比较解剖性节段切除术与楔形切除术用于高风险可手术的临床 I 期非小细胞肺癌患者:日本临床肿瘤学组研究 JCOG1909(ANSWER 研究)。
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单孔与三孔胸腔镜肺癌肺段切除术的围手术期及肿瘤学结局:一项倾向评分匹配分析
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Editorial: Bench Research Behind Lung Cancer Surgery.社论:肺癌手术背后的基础研究
Front Surg. 2022 Jun 21;9:936922. doi: 10.3389/fsurg.2022.936922. eCollection 2022.
The Effect of Tumor Size and Histologic Findings on Outcomes After Segmentectomy vs Lobectomy for Clinically Node-Negative Non-Small Cell Lung Cancer.肿瘤大小和组织学发现对临床淋巴结阴性非小细胞肺癌行解剖性肺段切除术与肺叶切除术术后结局的影响。
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