结核性脑膜炎：治疗起始时间对死亡率的影响
Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality.
作者信息
Soria Jaime, Chiappe Alfredo, Gallardo Jorge, Zunt Joseph R, Lescano Andres G
机构信息
Division of Infectious Diseases, University of Kentucky, Lexington, Kentucky, USA.
Northern Pacific Global Health Research Fellows Training Consortium, University of Washington, Seattle, Washington, USA.
出版信息
Open Forum Infect Dis. 2021 Jun 30;8(7):ofab345. doi: 10.1093/ofid/ofab345. eCollection 2021 Jul.
Abstract
We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality. The mortality of tuberculous meningitis patients was high and was associated with delay in initiation of treatment, older age, HIV infection, and higher disease severity at admission.
摘要
我们对确诊为结核性脑膜炎的成年住院患者进行了一项回顾性横断面研究，以确定开始治疗的时间对死亡率的影响。结核性脑膜炎患者的死亡率很高，且与治疗开始延迟、年龄较大、艾滋病毒感染以及入院时疾病严重程度较高有关。
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