[显著IgE升高的复发性葡萄球菌性皮炎：高IgE综合征]
[Recurrent staphylodermas in marked IgE elevation: the hyper-IgE syndrome].
作者信息
Huber A, Mietens C
机构信息
Universitäts-Kinderklinik, St. Josef Hospital Bochum.
出版信息
Klin Padiatr. 1987 Nov-Dec;199(6):445-6. doi: 10.1055/s-2008-1026836.
PMID:3431023
Abstract
This is a report of a 6-year-old boy with repeated staphylococcus infections especially in the hairy region of the head. Investigating the disease an extremely elevated IgE of 10,000 KU/l was found, specific IgE in RAST only at a low level. The immunologic investigations showed a reduction of the T-suppressor-cells and an increase of IgG levels. Defects of phagocytosis or chemotaxis could not be demonstrated.
摘要
这是一份关于一名6岁男孩的报告，该男孩反复发生葡萄球菌感染，尤其是头部毛发部位。在对该疾病进行调查时，发现其免疫球蛋白E（IgE）极度升高，达10,000KU/l，而放射性变应原吸附试验（RAST）中的特异性IgE仅处于低水平。免疫学检查显示T抑制细胞减少，免疫球蛋白G（IgG）水平升高。未发现吞噬作用或趋化性缺陷。
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