Williams C R, Geddes L A, Bourland J D, Furgason E S
William A. Hillenbrand Biomedical Engineering Center, Purdue University, West Lafayette, IN 47907.
Med Instrum. 1987 Dec;21(6):329-34.
We have designed a high-impedance (5000 omega-cm), tapered, gelled-pad, external cardiac pacing electrode that limits the migration of charges to the perimeter of a circular electrode and produces a more uniform current-density distribution than external cardiac pacing electrodes in clinical use. A computer simulation was developed that uses cylindrical coordinates to analyze the current-density distribution at the interface between the electrode and human tissue. Our computer simulation analyzed 32 different electrodes, and the results showed that the gelled-pad thickness, the gelled-pad taper, and the radius of the conducting disk were not significant parameters in determining the current-density distributions for low-resistivity electrodes. Those parameters were, however, significant for high-resistivity electrodes. We defined the optimum resistivity as that at which the tapered, gelled-pad electrode produces the most uniform current-density distribution and delivers the most current to human tissue. When evaluating electrodes at the optimum resistivity, we determined that the peak current density of the tapered, gelled-pad electrode was 50% lower than that of the clinically available electrodes, while delivering 58% more current to the human tissue.
我们设计了一种高阻抗(5000欧姆·厘米)、呈锥形、带有凝胶垫的体外心脏起搏电极,该电极可将电荷迁移限制在圆形电极的周边,并比临床使用的体外心脏起搏电极产生更均匀的电流密度分布。我们开发了一种计算机模拟程序,利用圆柱坐标来分析电极与人体组织界面处的电流密度分布。我们的计算机模拟分析了32种不同的电极,结果表明,对于低电阻率电极,凝胶垫厚度、凝胶垫锥度和导电盘半径并非决定电流密度分布的显著参数。然而,对于高电阻率电极,这些参数却很重要。我们将最佳电阻率定义为锥形凝胶垫电极产生最均匀电流密度分布并向人体组织输送最多电流时的电阻率。在以最佳电阻率评估电极时,我们确定锥形凝胶垫电极的峰值电流密度比临床可用电极低50%,同时向人体组织输送的电流多58%。