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经皮心脏起搏期间电流密度分布的建模

Modeling current density distributions during transcutaneous cardiac pacing.

作者信息

Panescu D, Webster J G, Stratbucker R A

机构信息

E.P. Technologies, Incorporated, Sunnyvale, CA 94086.

出版信息

IEEE Trans Biomed Eng. 1994 Jun;41(6):549-55. doi: 10.1109/10.293242.

Abstract

We developed a two-dimensional finite element model of a cross-section of the human thorax to study the current density distribution during transcutaneous cardiac pacing. The model comprises 964 nodes and 1842 elements and accounted for the electrical properties of eight different tissues or organs and also simulated the anisotropies of the intercostal muscles. The finite element software employed was a version for electrokinetics problems of Finite Element for Heat Transfer (FEHT) and we assessed the effects upon the efficacy of transcutaneous cardiac pacing of several electrode placements and sizes. To minimize pain in the chest wall and still be able to capture the heart, we minimized the ratio, R, between the current density in the thoracic wall (which causes pain) and the current density in the heart wall (which captures the heart). The best placement of the negative electrode was over the cardiac apex. The best placement of the positive electrode was under the right scapula, although other placements were nearly as good. The efficiency of pacing increased as electrode size increased up to 70 cm2 and showed little improvement for larger areas. Between different configurations of the precordial electrodes V1, V2, ..., V6 the most efficient configuration to pace with was V1 and V2 positive and V5 and V6 negative. A more efficient configuration uses an auxiliary electrode located at the right subscapular region.

摘要

我们建立了一个人体胸部横截面的二维有限元模型,以研究经皮心脏起搏期间的电流密度分布。该模型包含964个节点和1842个单元,考虑了八种不同组织或器官的电学特性,还模拟了肋间肌的各向异性。所使用的有限元软件是热传递有限元(FEHT)的一个用于电动问题的版本,并且我们评估了几种电极放置位置和尺寸对经皮心脏起搏效果的影响。为了使胸壁疼痛最小化且仍能捕获心脏,我们将胸壁(引起疼痛)的电流密度与心脏壁(捕获心脏)的电流密度之比R最小化。负极的最佳放置位置是在心脏尖部上方。正极的最佳放置位置是在右肩胛骨下方,不过其他位置的效果也差不多。起搏效率随着电极尺寸增加到70平方厘米而提高,对于更大的面积则改善不大。在前胸电极V1、V2、……、V6的不同配置中,最有效的起搏配置是V1和V2为正极,V5和V6为负极。一种更有效的配置是使用位于右肩胛下区域的辅助电极。

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