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导致心肌肌钙蛋白升高的循环嗜异性抗体：一种不常见的心肌病鉴别诊断。

Circulating Heterophile Antibodies Causing Cardiac Troponin Elevation: An Unusual Differential Diagnosis of Myocardial Disease.

作者信息

Graça Santos Luís, Ribeiro Carvalho Rita, Montenegro Sá Fernando, Soares Francisco, Pernencar Sidarth, Castro Ricardo, Morais João

机构信息

Department of Cardiology, Leiria Hospital Centre, Leiria, Portugal.

Department of Clinical Pathology, Leiria Hospital Centre, Leiria, Portugal.

出版信息

JACC Case Rep. 2020 Mar 18;2(3):456-460. doi: 10.1016/j.jaccas.2020.01.011. eCollection 2020 Mar.

DOI:10.1016/j.jaccas.2020.01.011
PMID:34317263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8311687/
Abstract

We present the case of a female patient who developed persistently elevated levels of cardiac troponin (cTn) after a previous episode of clinically presumed myocarditis. Extensive investigation concluded that the presence of heterophile antibodies was causing false positive cTn elevation. ().

摘要

我们报告了一例女性患者的病例，该患者在先前一次临床诊断为心肌炎的发作后，心肌肌钙蛋白（cTn）水平持续升高。广泛调查得出结论，嗜异性抗体的存在导致了cTn假阳性升高。（）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/90bdedc575b9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/717a0bf27db8/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/b4844b614ff2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/fab5760f5372/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/86af91ee441d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/1b654c36a360/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/90bdedc575b9/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/717a0bf27db8/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/b4844b614ff2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/fab5760f5372/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/86af91ee441d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/1b654c36a360/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/8311687/90bdedc575b9/gr5.jpg

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本文引用的文献

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Fourth Universal Definition of Myocardial Infarction (2018).心肌梗死的第四次全球定义（2018年）。
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2
Myocardial infarction with nonobstructive coronary arteries: a single-center retrospective study.非阻塞性冠状动脉所致心肌梗死：一项单中心回顾性研究
Coron Artery Dis. 2018 Sep;29(6):511-515. doi: 10.1097/MCA.0000000000000619.
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What to do when you question cardiac troponin values.当你对心肌肌钙蛋白值有疑问时该怎么办。
血清肌钙蛋白的临床生物化学
Diagnostics (Basel). 2024 Feb 9;14(4):378. doi: 10.3390/diagnostics14040378.
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The Dilemma Behind Negative Troponin: A Case Report.肌钙蛋白阴性背后的困境：一例报告
Cureus. 2023 Jan 30;15(1):e34377. doi: 10.7759/cureus.34377. eCollection 2023 Jan.
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On the Effect of Heterophilic Antibodies on Serum Levels of Cardiac Troponins: A Brief Descriptive Review.嗜异性抗体对心肌肌钙蛋白血清水平的影响：简要描述性综述
Life (Basel). 2022 Jul 24;12(8):1114. doi: 10.3390/life12081114.
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