Chaulin Aleksey Michailovich
Department of Cardiology and Cardiovascular Surgery, Samara State Medical University, 443099 Samara, Russia.
Department of Histology and Embryology, Samara State Medical University, 443099 Samara, Russia.
Life (Basel). 2022 Jul 24;12(8):1114. doi: 10.3390/life12081114.
Serum levels of cardiac troponins can be increased both with myocardial damage and in the absence of myocardial damage. In the second case, this is due to the influence of false-positive factors, among which heterophilic antibodies play a significant role. Understanding the causes of the formation of heterophilic antibodies, the features and mechanisms of their effect on serum levels of cardiac troponins, is an important condition for interpreting a false-positive result due to the influence of heterophilic antibodies. This brief, descriptive review presents the causes of heterophilic-antibodies formation and discusses their effect on serum levels of cardiac troponins.
心肌损伤时和无心肌损伤时，血清心肌肌钙蛋白水平均可升高。在后一种情况下，这是由于假阳性因素的影响，其中嗜异性抗体起重要作用。了解嗜异性抗体的形成原因、其对血清心肌肌钙蛋白水平影响的特点和机制，是解释嗜异性抗体影响导致的假阳性结果的重要条件。这篇简短的描述性综述介绍了嗜异性抗体的形成原因，并讨论了它们对血清心肌肌钙蛋白水平的影响。
