Department of Ophthalmology, Universidade Estácio de Sá, Rio de Janeiro, RJ, Brazil.
Arq Bras Oftalmol. 2021 Nov-Dec;84(6):549-553. doi: 10.5935/0004-2749.20210081.
To identify ocular manifestations in patients with Chikungunya fever in the chronic phase and describe their sociodemographic profile.
Patients with serologic confirmation of Chikungunya infection were included in this transverse study. All subjects underwent a comprehensive ophthalmologic evaluation, including specific lacrimal function tests (tear break-up time test, Schirmer test, and lissamine green).
Overall, 64 eyes of 32 patients were evaluated. Most patients were women (71.9%), with the mean age of 50.0 ±13.7 years. The mean interval between serologic confirmation and the examination was 12.7 ±7.7 months. Twenty patients (62%) presented with dry eye. No statistically significant association was observed between dry eye and infection diagnosis time (p=0.5546), age (p=0.9120), sex (p=1.00), race (p=0.2269), arthralgia in acute infection (p=0.7930), retro-orbital pain (p=0.3066), and conjunctivitis (p=1.00).
Dry eye was the most prevalent manifestation observed. No signs of intraocular inflammation and affected visual acuity were observed.
确定基孔肯雅热慢性期患者的眼部表现，并描述其社会人口学特征。
本横断面研究纳入了血清学确认的基孔肯雅感染患者。所有患者均接受了全面的眼科评估，包括特定的泪液功能测试（泪膜破裂时间测试、泪液分泌试验和丽丝胺绿染色）。
共评估了 32 例患者的 64 只眼。大多数患者为女性（71.9%），平均年龄为 50.0±13.7 岁。血清学确诊与检查之间的平均间隔为 12.7±7.7 个月。20 名患者（62%）出现干眼症。干眼症与感染诊断时间（p=0.5546）、年龄（p=0.9120）、性别（p=1.00）、种族（p=0.2269）、急性感染时的关节痛（p=0.7930）、眼眶后疼痛（p=0.3066）和结膜炎（p=1.00）之间均无统计学显著相关性。
干眼症是观察到的最常见表现。未观察到眼内炎症和受影响的视力迹象。
