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[2001年至2018年哥伦比亚波哥大主动脉缩窄的患病率。诊断需要改进]

[Prevalence of aortic coarctation in Bogotá-Colombia from 2001 to 2018. The diagnostic needs to improve].

作者信息

Ardila Daniel F, Rincón-Montana Angela G, García-Pérez Laura D, Gracia Gloria, Zarante Ignacio

机构信息

School of Medicine, Pontificia Universidad Javeriana, Bogotá, Colombia.

Secretaría de Salud de Bogotá, Bogotá, Colombia.

出版信息

Arch Cardiol Mex. 2022 Apr 4;92(2):196-202. doi: 10.24875/ACM.20000515.

Abstract

OBJECTIVES

Aortic coarctation is the most frequent structural anomaly out of congenital heart diseases. This congenital defect is an important cause of death worldwide. We sought to determine the prevalence of aortic coarctation in Colombia and whether new policies have had an impact on its diagnosis.

METHODS

In this study information from the Bogotá birth defect surveillance program during the years 2001-2018 from 63 hospitals was used. 537,026 live births of any weight and stillbirths of any weight were analyzed. The information was stored in a database on the servers of the Health Secretariat and the Pontificia Universidad Javeriana. We analyzed the presence of aortic coarctation according to the newborn's sex, weight, size, mother's age, and gestational age at the time of birth and when coarctation is accompanied by other types of congenital malformations.

RESULTS

The prevalence of aortic coarctation in Bogotá during the years 2001-2018 found in this study was 1.25 in 10,000 live births. We also found that prevalence of aortic coarctation in Bogotá changes throughout the years having a significant increase in the year 2018 with 6.57 cases in 10,000 live births.

CONCLUSIONS

This prevalence is higher than the one found in a study with data from 2001 to 2014, which suggests an improvement in the country's epidemiological surveillance and medical training. However, the prevalence found in Bogotá is still lower compared to the prevalence worldwide and from other continents, the prevalence for Latinamerica was significantly lower as compared to those in Asia, Europe, and United States so we emphasize the importance of continuing with improvements, such as standardizing screening methods and sensitivity of said methods in a local scale as well as a continental scale.

摘要

目的

主动脉缩窄是先天性心脏病中最常见的结构异常。这种先天性缺陷是全球范围内一个重要的死亡原因。我们试图确定哥伦比亚主动脉缩窄的患病率以及新政策是否对其诊断产生了影响。

方法

在本研究中,使用了2001年至2018年期间来自波哥大63家医院的出生缺陷监测项目的信息。分析了537,026例任何体重的活产儿和任何体重的死产儿。这些信息存储在卫生秘书处和哈韦里亚纳教皇大学服务器上的数据库中。我们根据新生儿的性别、体重、体型、母亲年龄、出生时的孕周以及缩窄是否伴有其他类型的先天性畸形来分析主动脉缩窄的存在情况。

结果

本研究发现2001年至2018年期间波哥大主动脉缩窄的患病率为每10,000例活产儿中有1.25例。我们还发现波哥大主动脉缩窄的患病率多年来有所变化,2018年显著增加,每10,000例活产儿中有6.57例。

结论

这一患病率高于一项使用2001年至2014年数据的研究中发现的患病率,这表明该国的流行病学监测和医学培训有所改善。然而,与全球和其他各大洲的患病率相比,波哥大发现的患病率仍然较低,与亚洲、欧洲和美国相比,拉丁美洲的患病率明显较低,因此我们强调继续改进的重要性,例如在地方和大陆范围内规范筛查方法及其敏感性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ad3/9005175/e920da8a7c75/6936AX212-ACM-92-196-g001.jpg

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