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正颌手术是否需要有创动脉监测引导的低血压麻醉?——三级医院正颌手术麻醉实践与术中失血的回顾性分析

Is hypotensive anaesthesia guided by invasive intraarterial monitoring required for orthognathic surgery? - A retrospective review of anaesthetic practice and intraoperative blood loss in orthognathic surgery in a tertiary hospital.

作者信息

Lee Yi Lin, Thangavelautham Suhitharan, Harikrishnan Sudha, Karthekeyan Ranjith, Kothandan Harikrishnan

机构信息

Department of Surgical Intensive Care, Singapore General Hospital, Chennai, Tamil Nadu, India.

Department of Anaesthesiology, Singapore General Hospital, Tamil Nadu, India.

出版信息

Indian J Anaesth. 2021 Jul;65(7):525-532. doi: 10.4103/ija.IJA_201_21. Epub 2021 Jul 23.

Abstract

BACKGROUND AND AIMS

Orthognathic surgeries for maxillofacial deformities are commonly performed globally and are associated with significant blood loss. This can distort the surgical field and necessitate blood transfusion with its concomitant risks. We aimed to review if invasive intraarterial (IA) line monitoring and/or hypotensive anaesthesia is required for orthognathic surgeries, and their effects on intraoperative blood loss and transfusion requirements.

METHODS

This was a retrospective observational study conducted in patients admitted for orthognathic surgeries in a public tertiary hospital. Anaesthetic techniques and intraoperative haemodynamics were studied for their effects on intraoperative blood loss.

RESULTS

The data from 269 patients who underwent orthognathic-bimaxillary surgeries was analysed. Inhalational anaesthetic combined with remifentanil was administered for 86.6%, total intravenous anesthesia to 11.2% patients, while the rest received inhalational anaesthesia. Hypotensive anaesthesia was achieved in 48 subjects (17.8%) and associated with shorter duration of surgery (349 vs 378 min, = 0.02) and a trend towards lower blood loss (874 mL vs 1000 mL, = 0.058) but higher transfusion requirement (81.3% vs 58.8%, = 0.004). An IA line was used in 119 patients (44.2%) and was not associated with a higher probability of achieving hypotensive anaesthesia (19.3% vs 16.7%, = 0.06). However, less blood loss (911 vs 1029 mL, = 0.05) occurred compared to noninvasive blood pressure monitoring.

CONCLUSION

Invasive blood pressure monitoring is as effective as noninvasive methods to achieve hypotensive anaesthesia. It does not aid in achieving lower target blood pressure. There is a lack of association between a reduction in blood loss and higher blood transfusion during hypotensive anaesthesiaand thiswill require further evaluation.

摘要

背景与目的

正颌手术用于治疗颌面部畸形,在全球范围内广泛开展,且常伴有大量失血。这会使手术视野变形,还需要输血,而输血存在相应风险。我们旨在探讨正颌手术是否需要有创动脉(IA)置管监测和/或控制性降压麻醉,以及它们对术中失血和输血需求的影响。

方法

这是一项在一家公立三级医院对接受正颌手术患者进行的回顾性观察研究。研究麻醉技术和术中血流动力学对术中失血的影响。

结果

分析了269例行正颌双颌手术患者的数据。86.6%的患者采用吸入麻醉联合瑞芬太尼,11.2%的患者采用全静脉麻醉,其余患者采用吸入麻醉。48名受试者(17.8%)实施了控制性降压麻醉,其手术时间较短(349分钟对378分钟,P = 0.02),且有失血减少的趋势(874毫升对1000毫升,P = 0.058),但输血需求更高(81.3%对58.8%,P = 0.004)。119名患者(44.2%)使用了IA置管,其实现控制性降压麻醉的概率并不更高(19.3%对16.7%,P = 0.06)。然而,与无创血压监测相比,术中失血更少(911毫升对1029毫升,P = 0.05)。

结论

有创血压监测在实现控制性降压麻醉方面与无创方法同样有效。它无助于达到更低的目标血压。控制性降压麻醉期间失血减少与输血增加之间缺乏相关性,这需要进一步评估。

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