通过氢原子夺取或炔烃去质子化从钛酰胺生成掩蔽钛中间体：钛催化氮烯偶联转移氢化的一个例子。
Generation of Masked Ti Intermediates from Ti Amides via -H Abstraction or Alkyne Deprotonation: An Example of Ti-Catalyzed Nitrene-Coupled Transfer Hydrogenation.
作者信息
Pearce Adam J, Cheng Yukun, Dunscomb Rachel J, Tonks Ian A
机构信息
Department of Chemistry, University of Minnesota-Twin Cities, Minneapolis, Minnesota 55455, United States.
出版信息
Organometallics. 2020 Nov 9;39(21):3771-3774. doi: 10.1021/acs.organomet.0c00577. Epub 2020 Oct 20.
Abstract
Simple Ti amide complexes are shown to act as sources for masked Ti intermediates via several pathways, as demonstrated through the investigation of a unique Ti-catalyzed nitrene-coupled transfer hydrogenation of 3-hexyne. This reaction proceeds through reduction of azobenzene by a masked Ti catalyst, wherein both amines and 3-hexyne can serve as the hydrogen source/reductant for Ti by forming putative titanaziridines via -H abstraction or putative titanacyclopentynes via protonolysis, respectively.
摘要
简单的钛酰胺配合物通过多种途径被证明可作为掩蔽钛中间体的来源，这是通过对独特的钛催化3-己炔的氮烯偶联转移氢化反应的研究得到证实的。该反应通过掩蔽钛催化剂还原偶氮苯进行，其中胺和3-己炔都可以分别通过氢原子提取形成假定的钛氮杂环丙烷或通过质子解形成假定的钛杂环戊炔，作为钛的氢源/还原剂。
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