Farsad Mohsen, Ambrosini Valentina, Nanni Cristina, Castellucci Paolo, Boschi Stefano, Rubello Domenico, Fabbri Mario, Franchi Roberto, Fanti Stefano
UO Medicina Nucleare, Università di Bologna, Policlinico S. Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.
Nucl Med Commun. 2005 Sep;26(9):827-30. doi: 10.1097/01.mnm.0000175786.27423.42.
Integrated positron emission tomography/computed tomography (PET/CT) systems represent a major development allowing functional and anatomical information to be acquired in a single examination session and therefore providing a more accurate definition of suspected lesion characteristics. Together with the increasing number of clinical settings in which PET/CT scans have been advocated, however, pitfalls in image interpretation have been reported.
Four female subjects presenting a focal area of increased F-fluorodeoxyglucose (F-FDG) uptake with no evidence of a corresponding CT abnormality were included in the study. PET/CT scans were performed in all cases after the administration of 5.3 MBq . kg of F-FDG through a venous cannula.
Focal high uptake of F-FDG was observed in lung lesions without anatomical counterparts on CT in four female cases. The only common feature to all was the paravenous injection of the radiotracer.
The lesions detected by PET may be related to distal lung microembolism originating from the site of paravenous injection.
一体化正电子发射断层扫描/计算机断层扫描（PET/CT）系统是一项重大进展，能够在单次检查中获取功能和解剖学信息，从而更准确地界定可疑病变的特征。然而，随着PET/CT扫描在越来越多临床场景中得到应用，图像解读中的陷阱也被报道出来。
本研究纳入了4名女性受试者，她们的氟代脱氧葡萄糖（F-FDG）摄取出现局灶性增加，而CT检查未发现相应异常。所有病例均通过静脉插管注入5.3 MBq·kg的F-FDG后进行PET/CT扫描。
在4例女性病例中，肺部病变出现了F-FDG局灶性高摄取，而CT上没有相应的解剖学对应物。所有病例唯一的共同特征是放射性示踪剂经静脉旁注射。
PET检测到的病变可能与静脉旁注射部位产生的远端肺微栓塞有关。
