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奥马珠单抗相关性嗜酸性肉芽肿性多血管炎:是病因还是巧合?

Omalizumab-associated eosinophilic granulomatosis with polyangiitis: cause or coincidence?

机构信息

Respiratory Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK

Respiratory Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK.

出版信息

BMJ Case Rep. 2021 Jul 29;14(7):e240078. doi: 10.1136/bcr-2020-240078.

Abstract

Omalizumab is an anti-IgE monoclonal antibody used in severe allergic asthma. Herein, we describe a case of eosinophilic granulomatosis with polyangiitis, which manifested 3 months after initiation of omalizumab therapy, while maintenance corticosteroid therapy dose was unchanged.

摘要

奥马珠单抗是一种用于治疗严重过敏性哮喘的抗 IgE 单克隆抗体。本文描述了一例奥马珠单抗治疗 3 个月后发生嗜酸性肉芽肿性多血管炎的病例,此时维持皮质类固醇激素治疗剂量未变。

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