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心血管疾病风险全谱中的危险因素控制:西班牙裔社区健康研究/拉丁裔研究(HCHS/SOL)的研究结果

Risk factor control across the spectrum of cardiovascular risk: Findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

作者信息

Rodriguez Fatima, Lee Un Jung, Barone Nicholas, Swett Katrina, Lopez Lenny, Cheng Susan, Daviglus Martha L, Hanna David B, Espinoza Giacinto Rebeca A, Arguelles William, Cai Jianwen, Talavera Gregory A, Rodriguez Carlos J

机构信息

Division of Cardiovascular Medicine and the Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.

Departments of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.

出版信息

Am J Prev Cardiol. 2021 Jan 13;5:100147. doi: 10.1016/j.ajpc.2021.100147. eCollection 2021 Mar.

DOI:10.1016/j.ajpc.2021.100147
PMID:34327490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8315414/
Abstract

BACKGROUND

Presence of cardiovascular disease (CVD) risk factors (RFs) should prompt patients and their providers to work aggressively towards controlling those that are modifiable. The extent to which a greater CVD RF burden is related to CVD RF control in a contemporary and diverse Hispanic/Latino population is not well-understood.

METHODS

Using multicenter community-based data from the Hispanic Community Health Study/Study of Latinos, we assessed the self-reported prevalence of hypertension, hypercholesterolemia, diabetes, and prevalent CVD (ischemic heart disease or stroke). We used contemporaneous guidelines to define RF control. Multivariable logistic regression for complex survey sampling was used to examine whether having more CVD RFs was associated with CVD RF control (adjusting for age, sex, Hispanic background group, education, and health insurance).

RESULTS

Our sample included 8521 participants with at least one CVD RF or prevalent CVD. The mean age in HCHS/SOL target population was 49 (SE 0.3) years and 56% were women. Frequency of one, two, or three self-reported CVD RFs was 57%, 26%, 8%, respectively, and overall 9% of participants had prevalent CVD. After adjusting for sociodemographic factors, compared to those reporting one CVD RF, individuals with three CVD RFs were the least likely to have blood pressure, cholesterol, and glucose optimally controlled (odds ratio [OR]: 0.56; 95% confidence interval [CI]: 0.40-0.80). However, those with prevalent CVD were more likely to have all three risk factors controlled, (OR: 1.43; 95% CI: 1.01-2.01).

CONCLUSION

Hispanic/Latino adults with three major CVD RFs represent a group with poor overall CVD RF control. Secondary CVD prevention fares better. The potential contributors to inadequate CVD RF control in this highly vulnerable group warrants further investigation.

摘要

背景

心血管疾病(CVD)风险因素(RFs)的存在应促使患者及其医护人员积极努力控制那些可改变的风险因素。在当代多样化的西班牙裔/拉丁裔人群中,较高的CVD风险因素负担与CVD风险因素控制之间的关联程度尚未得到充分理解。

方法

利用西班牙裔社区健康研究/拉丁裔研究的多中心社区数据,我们评估了高血压、高胆固醇血症、糖尿病以及现患CVD(缺血性心脏病或中风)的自我报告患病率。我们使用同期指南来定义风险因素控制。采用复杂抽样调查的多变量逻辑回归分析,以检验拥有更多CVD风险因素是否与CVD风险因素控制相关(调整年龄、性别、西班牙裔背景组、教育程度和医疗保险)。

结果

我们的样本包括8521名至少有一个CVD风险因素或现患CVD的参与者。西班牙裔社区健康研究/拉丁裔研究目标人群的平均年龄为49(标准误0.3)岁,56%为女性。自我报告的一种、两种或三种CVD风险因素的频率分别为57%、26%、8%,总体上9%的参与者患有现患CVD。在调整社会人口学因素后,与报告一种CVD风险因素的人相比,有三种CVD风险因素的个体血压、胆固醇和血糖得到最佳控制的可能性最小(比值比[OR]:0.56;95%置信区间[CI]:0.40 - 0.80)。然而,患有现患CVD的人更有可能使所有三种风险因素得到控制(OR:1.43;95% CI:1.01 - 2.01)。

结论

具有三种主要CVD风险因素的西班牙裔/拉丁裔成年人总体上CVD风险因素控制较差。二级CVD预防效果较好。在这个高度脆弱的群体中,CVD风险因素控制不足的潜在原因值得进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3888/8315414/140705c89bc9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3888/8315414/140705c89bc9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3888/8315414/140705c89bc9/gr1.jpg

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