Department of Dental Specialties, Mayo Clinic, Rochester, Minnesota, USA.
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
Spec Care Dentist. 2022 Jan;42(1):86-90. doi: 10.1111/scd.12638. Epub 2021 Jul 30.
Oral cavity lymphomas constitute only 3% of all lymphomas in the general population but are the third most common oral malignancy. A 67-year-old female with a history of osteoporosis, Graves' disease and non-Hodgkin's lymphoma was referred to the Department of Dental Specialties with a chief complaint of persistent soft tissue swelling facial to the maxillary incisors of possible non-odontogenic origin. To expedite care, the patient was first seen via teledentistry and subsequently appointed for an in-person evaluation and treatment. Examination revealed 1-3 mm probing depths and a firm, non-tender, non-fluctuant mass in the facial soft tissues approximating teeth nos. 7-10. Biopsy of the affected area was performed. A diagnosis of recurrent follicle center cell lymphoma, a form of non-Hodgkin's lymphoma, was rendered. The patient was subsequently referred to the Oncology and Hematology team, followed for 6 weeks and remained symptom-free. This case underlies the importance of teledentistry to expedite care and manage patient expectations. Additionally, it also underscores the importance of microscopic examination of tissue samples from oral lesions that appear non-odontogenic in nature and reinforces the role of dentistry in uncovering the oral-systemic link.
口腔淋巴瘤仅占普通人群中所有淋巴瘤的 3%，但却是第三大常见的口腔恶性肿瘤。一位 67 岁的女性，既往有骨质疏松症、格雷夫斯病和非霍奇金淋巴瘤病史，因上颌切牙前持续软组织肿胀，可能为非牙源性起源，到牙科专科就诊。为了加快治疗速度，患者首先通过远程牙科进行了初步检查，随后安排了亲自就诊和治疗。检查发现面部软组织中有 1-3 毫米的探诊深度和一个坚硬、无触痛、无波动的肿块，大致位于 7-10 号牙齿处。对受影响的区域进行了活检。诊断为复发性滤泡中心细胞淋巴瘤，一种非霍奇金淋巴瘤。随后，患者被转介到肿瘤和血液科团队，随访 6 周，且无任何症状。这个病例强调了远程牙科在加快治疗速度和管理患者期望方面的重要性。此外，它还强调了对非牙源性口腔病变组织样本进行显微镜检查的重要性，并强化了牙科在揭示口腔-全身联系方面的作用。
