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患有乳腺大囊肿的女性血清及囊内甲状腺素(T4)和三碘甲状腺原氨酸(T3)水平

Serum and intracystic levels of thyroxine (T4) and triiodothyronine (T3) in women with breast macrocysts.

作者信息

Cupceancu B, Pop A, Purice M, Mogoş I

机构信息

C. I. Parhon Institute of Endocrinology, Bucharest, Romania.

出版信息

Endocrinologie. 1987 Oct-Dec;25(4):209-15.

PMID:3432987
Abstract

In 15 patients with a total of 22 breast macrocysts serum and intracystic T4 and T3 and intracysts TSH were concomitantly radioimmunoassayed (using a technique with polyethylene glycol (PEG) for T3, T4, and a double antibody technique for TSH). While in most cysts (17/22) the T4 values were under those in the serum, in 21 cysts T3 was 2-18 times above the serum values. Intracystic TSH was at the lower limit of the normal serum TSH values whereas prolactin (PRL) and thyroglobulin (TGL) assayed in several cysts were not different from their serum value. It suggests that breast macrocysts are able to concentrate or even produce triiodothyronine.

摘要

对15例共有22个乳腺大囊肿的患者,同时采用放射免疫法检测血清及囊内的T4、T3以及囊内促甲状腺激素(TSH)(检测T3、T4时采用聚乙二醇(PEG)技术,检测TSH时采用双抗体技术)。虽然多数囊肿(17/22)的T4值低于血清中的T4值,但21个囊肿的T3值高于血清值2至18倍。囊内TSH处于正常血清TSH值的下限,而在几个囊肿中检测的催乳素(PRL)和甲状腺球蛋白(TGL)与血清值无差异。这表明乳腺大囊肿能够浓缩甚至产生三碘甲状腺原氨酸。

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