Clinical Research Unit for Anxiety and Depression (CRUfAD), St. Vincent's Hospital, Level 4 O'Brien Centre, 394- 404 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia; School of Psychology, Faculty of Science, University of New South Wales, Sydney, NSW, 2052, Australia.
Clinical Research Unit for Anxiety and Depression (CRUfAD), St. Vincent's Hospital, Level 4 O'Brien Centre, 394- 404 Victoria Street, Darlinghurst, Sydney, NSW, 2010, Australia; School of Psychiatry, Faculty of Medicine, University of New South Wales, Sydney, NSW, 2052, Australia.
J Affect Disord. 2021 Nov 1;294:483-490. doi: 10.1016/j.jad.2021.07.076. Epub 2021 Jul 23.
Rumination and worry, both forms of repetitive negative thinking (RNT), have been implicated in the onset, maintenance, severity, and relapse risk of depression and anxiety disorders. Despite promising initial findings for internet-delivered interventions targeting both rumination and worry simultaneously, no studies have investigated treatment effects in an adult population or when delivered in a brief, unguided format. We developed a 3-lesson unguided online treatment program targeting both rumination and worry and evaluated the adherence and effectiveness in Australian adults using an open pilot trial.
Adult participants (N=26) experiencing elevated levels of RNT completed the online program over 6-weeks. Outcomes were assessed at baseline, post-treatment, and 1-month follow-up. Intention-to-treat linear mixed models were used to examine effects on RNT, anxiety, depression, and general psychological distress.
Of the 26 participants who started the program, 18 completed all three lessons (69.2% completion rate). Large within-subject effect sizes were found between pre- and post-treatment for RNT (Hedges' g= 2.26) and symptoms of depression (g = 1.04), generalised anxiety (g = 1.82) and distress (g = 0.93). Treatment effects were maintained at 1-month follow-up.
No long-term follow-up, exclusion of severely depressed individuals.
This is the first study to evaluate a brief, unguided internet intervention targeting both rumination and worry in adults. The results provide promising preliminary evidence for the feasibility and acceptability of the online program. Randomised controlled trials are needed to evaluate treatment efficacy compared to a control group and to investigate long-term outcomes.
反刍和担忧,都是重复消极思维(RNT)的形式,与抑郁和焦虑障碍的发病、维持、严重程度和复发风险有关。尽管针对反刍和担忧同时进行的互联网干预有初步的研究结果,但没有研究在成年人群中或在简短、无指导的形式下进行治疗效果的研究。我们开发了一个 3 课的无指导在线治疗方案,针对反刍和担忧,并通过一个开放的试点试验评估了澳大利亚成年人的依从性和效果。
有高水平 RNT 的成年参与者(N=26)在 6 周内完成了在线方案。在基线、治疗后和 1 个月随访时评估结果。使用意向性治疗线性混合模型来检验 RNT、焦虑、抑郁和一般心理困扰的效果。
在开始该方案的 26 名参与者中,有 18 人完成了所有 3 课(完成率为 69.2%)。在治疗前和治疗后之间,反刍和抑郁(g=1.04)、广泛性焦虑(g=1.82)和困扰(g=0.93)的症状出现了大的个体内效应大小。治疗效果在 1 个月随访时保持不变。
没有长期随访,排除了严重抑郁的个体。
这是第一项评估针对成人的简短、无指导的针对反刍和担忧的互联网干预的研究。结果为该在线方案的可行性和可接受性提供了有希望的初步证据。需要进行随机对照试验,以评估与对照组相比的治疗效果,并研究长期结果。