Allison M C, Dick R, Pounder R E
Academic Dept. of Medicine, Royal Free Hospital, London, U.K.
Scand J Gastroenterol. 1987 Dec;22(10):1277-80. doi: 10.3109/00365528708996476.
The object of this study was to assess faecal distribution and faecal stasis in patients with ulcerative colitis and healthy control subjects and to relate the findings to the activity and extent of the disease. Each subject ingested 10 radiopaque markers daily for 13 days and attended for a plain abdominal roentgenogram on the 14th day. Patients with active ulcerative proctocolitis retained significantly fewer markers in the whole colon (median values, 11 versus 24 markers) due to a decrease of markers in the left colon (median values, 3 versus 13 markers) compared with the control group (p less than 0.05). Patients with either proctitis or colitis in remission and control subjects retained similar numbers of markers. The results of this study suggest that, as a group, patients with proctocolitis do not have proximal faecal stasis.
本研究的目的是评估溃疡性结肠炎患者和健康对照者的粪便分布及粪便淤滞情况，并将研究结果与疾病的活动度和范围相关联。每位受试者连续13天每天摄入10个不透X线的标志物，并在第14天接受腹部平片检查。与对照组相比，活动性溃疡性直肠结肠炎患者整个结肠内保留的标志物显著减少（中位数分别为11个和24个标志物），原因是左半结肠内的标志物减少（中位数分别为3个和13个标志物）（p<0.05）。处于缓解期的直肠炎或结肠炎患者与对照者保留的标志物数量相似。本研究结果表明，作为一个群体，直肠结肠炎患者不存在近端粪便淤滞。
