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接种 COVID-19 疫苗后的吉兰-巴雷综合征。

Guillain-Barré syndrome after COVID-19 vaccination.

机构信息

Department of Neurosciences, Mater Dei Hospital, Msida, Malta

Department of Medicine, University of Malta, Msida, Malta.

出版信息

BMJ Case Rep. 2021 Jul 30;14(7):e244125. doi: 10.1136/bcr-2021-244125.

Abstract

We report a case of Guillain-Barré syndrome (GBS) occurring soon after the first dose of Vaxzevria (previously known as COVID-19 vaccine AstraZeneca). Thus far, there has been no evidence of an increased risk of GBS resulting from either COVID-19 infection nor from COVID-19 vaccines; however, individual cases and population cohorts should be scrutinised, in order to ensure the constant evaluation of such risks. It is as yet not possible to draw conclusions about any significant association between COVID-19 vaccination and GBS. A temporal correlation does not imply, and should not be deemed to signify, causality. However, it is important to remain vigilant, so that any potential increased risk is properly evaluated. The specific presentation of bifacial weakness as the initial symptom may be a characteristic feature of GBS in the context of recent COVID-19 vaccination.

摘要

我们报告了一例在接种第一剂 Vaxzevria(以前称为 COVID-19 疫苗阿斯利康)后不久发生的格林-巴利综合征(GBS)病例。到目前为止,没有证据表明 COVID-19 感染或 COVID-19 疫苗会增加 GBS 的风险;然而,应仔细审查个别病例和人群队列,以确保对这些风险进行持续评估。目前还不可能得出关于 COVID-19 疫苗接种与 GBS 之间存在任何显著关联的结论。时间相关性并不意味着,也不应被视为表示因果关系。然而,保持警惕很重要,以便对任何潜在的风险增加进行适当评估。作为初始症状的双侧面部无力的特定表现可能是最近 COVID-19 疫苗接种背景下 GBS 的一个特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c30/8327820/16445578a9d5/bcr-2021-244125f01.jpg

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