Department of Medicine, Federal Medical Centre, Asaba, Delta State, Nigeria.
Department of Medicine, University of Benin Teaching Hospital, Benin City, Edo State, Nigeria.
West Afr J Med. 2021 Jul 29;38(7):646-654.
Vitiligo is a pigmentary disorder of the skin with varied presentation across different populations. It may be associated with autoimmune conditions like type I diabetes mellitus, thyroiditis etc. This study sought to describe the clinical patterns of vitiligo amongst patients in Benin City, Nigeria.
This was a cross sectional study among adults with vitiligo consecutively recruited from the dermatology clinic at University of Benin Teaching Hospital, Benin City. Diagnosis of vitiligo was largely clinical. Data was obtained using a questionnaire and analyzed using SSPS version 21.0. Categorical and discrete variables were analyzed using Chi square, Fisher's Exact, T-Test and ANOVA. p-value of <0.05 was considered significant.
A total of 40 patients were recruited for this study with males accounting for 24 (60%) of the study population. The mean age for the study group was 38.43 12.94. Non Segmental Vitiligo was more prevalent 27(67.5%) while vitiligo vulgaris was the most common clinical variant in this study 19(47.5%).Lesions occurred mostly on the exposed parts of the body (87.5%) but the mean VASI score was 4.81. Diabetes mellitus and alopecia areata were observed in 25% of vitiligo patients. Kobnerization was more on the extremities (p 0.034) while leukotrichia was more on the face and the trunk (p 0.046 and 0.005 respectively).
The pattern of vitiligo differ across diverse populations. The clinical presentation of vitiligo in this study showed some differences from similar studies and therefore suggests for more studies in order to have a consensus on presentation of this disorder.
白癜风是一种皮肤色素紊乱疾病，在不同人群中的表现各不相同。它可能与自身免疫性疾病有关，如 1 型糖尿病、甲状腺炎等。本研究旨在描述尼日利亚贝宁城患者的白癜风临床模式。
这是一项横断面研究，对象为连续招募自贝宁大学教学医院皮肤科诊所的成年白癜风患者。白癜风的诊断主要基于临床。使用问卷获得数据，并使用 SSPS 版本 21.0 进行分析。使用卡方检验、Fisher 精确检验、T 检验和 ANOVA 分析分类和离散变量。p 值<0.05 被认为具有统计学意义。
共有 40 名患者被纳入本研究，男性占研究人群的 24 人（60%）。研究组的平均年龄为 38.43 ± 12.94 岁。非节段性白癜风更为常见，有 27 人（67.5%），而寻常型白癜风是本研究中最常见的临床变异型，有 19 人（47.5%）。病变主要发生在暴露部位（87.5%），但平均 VASI 评分为 4.81。糖尿病和斑秃在 25%的白癜风患者中观察到。肢端的 Kobner 现象更为常见（p<0.034），而白发主要发生在面部和躯干（p<0.046 和 0.005 分别）。
不同人群的白癜风模式存在差异。本研究中白癜风的临床表现与类似研究存在一些差异，因此需要更多的研究以达成对该疾病表现的共识。
