Onunu Abel N, Kubeyinje Emmanuel P
Dermatology and Venereology Unit, Department of Medicine, University of Benin Teaching Hospital, Benin City, Nigeria.
Int J Dermatol. 2003 Oct;42(10):800-2. doi: 10.1046/j.1365-4362.2003.01908.x.
There is a paucity of reports on vitiligo in sub-Saharan Africa.
To define the clinical and epidemiologic pattern of vitiligo in the Nigerian African.
We examined all new cases of vitiligo seen in the Dermatology Unit of the University of Benin Teaching Hospital (UBTH) over a 14-year period: January 1985 to December 1998.
Three hundred and fifty-one patients with vitiligo, representing 3.2% of new dermatologic cases, were enrolled. The study group was made up of 153 males and 198 females, giving a sex ratio of 1 : 1.3. The peak incidence of vitiligo was in the second and third decades of life, and the most common form of presentation was the localized focal type (77%), followed by the segmental type (12.5%) and the generalized form (10.5%). Common sites affected were the limbs (32%), trunk (23.8%), face (18.2%), head and neck (9.1%), and the mucous membranes (7.4%). There was a positive family history of vitiligo in 18% of subjects and 3.4% had systemic diseases, such as diabetes mellitus (1.7%), anemia (0.8%), hyperthyroidism (0.6%), and leukemia (0.3%).
Vitiligo on darkly pigmented skin is often a very striking disease. Our findings show that the pattern of vitiligo is similar to that reported from other parts of the world. The high level of social stigmatization is due to confusion with leprosy.
关于撒哈拉以南非洲地区白癜风的报道较少。
明确尼日利亚非洲人群中白癜风的临床和流行病学模式。
我们检查了1985年1月至1998年12月这14年间在贝宁大学教学医院皮肤科就诊的所有白癜风新病例。
共纳入351例白癜风患者,占皮肤科新病例的3.2%。研究组由153名男性和198名女性组成,性别比为1 : 1.3。白癜风的发病高峰在人生的第二个和第三个十年,最常见的表现形式是局限性点状型(77%),其次是节段型(12.5%)和泛发型(10.5%)。常见受累部位为四肢(32%)、躯干(23.8%)、面部(18.2%)、头颈部(9.1%)和黏膜(7.4%)。18%的受试者有白癜风家族史阳性,3.4%患有全身性疾病,如糖尿病(1.7%)、贫血(0.8%)、甲状腺功能亢进(0.6%)和白血病(0.3%)。
深色皮肤的白癜风往往是一种非常显著的疾病。我们的研究结果表明,白癜风的模式与世界其他地区报道的相似。社会高度污名化是由于与麻风病混淆所致。